Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obta...

Lung gene therapy for cystic fibrosis disease has not been successful due to several challenges such as the absence of an appropriate vector. Therefore, optimal delivery of emerging therapeutics to airway epithelial cells demands suitable non-viral systems. In this work, we describe the formulation and the physicochemical investigation of biocompatible and biodegradable polymeric nanoparticles ...

The delivery of drugs and active agents to the skin by formulations containing nanoparticles is a topic of considerable current interest. A number of studies have shown important advantages of these nanostructure-based delivery systems over conventional formulations. This review describes the composition, preparation, and characteristics of a wide range of novel vectors, including nanoemulsions...

Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal in designing drug delivery systems. Over the past few decades, there has been considerable interest in developing biodegradable dr...

While polymeric nanocarriers are widely used in medicine for controlled release and site-specific delivery, few reports have applied such delivery methods within agriculture, despite the urgent need for specific delivery of pesticides and nutrients. We report the synthesis of stimuli-responsive and biodegradable polymeric nanocarriers designed for delivery to the phloem of plants and describe m...

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Polymeric multilayer capsules have emerged as a novel drug delivery platform. These capsules are fabricated through layer-by-layer sequential deposition of polymers onto a sacrificial core template followed by the decomposition of this core yielding hollow capsules. The resulting nanometer thin membrane is permselective, allowing diffusion of water and ions but excluding larger molecules. Moreo...

nanotechnology has changed our lives dramatically and influenced every sector of the research, engineering and also business community. nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles, that measure in nanometer. in other words, nanotechnology is the art of characterizing, manipulating and organizing matter systemically, at the nanometer scale, which h...

There is a great potential in combining carrier-free crystalline-based drug delivery systems (DDSs) within polymeric implants/scaffolds manner that preserves each components' independent functionality, stability, and advantages. We believe this will open new avenues research as well accelerate polymers DDSs developments.

The oral route for drug delivery is regarded as the optimal route for achieving therapeutic benefits owing to increased patient compliance. Despite phenomenal advances in injectable, transdermal, nasal and other routes of administration, the reality is that oral drug delivery remains well ahead of the pack as the preferred delivery route. Nanocarriers can overcome the major challenges associate...