نتایج جستجو برای: polymyxins

تعداد نتایج: 1612  

2017
Nathalie Tijet Diego Faccone Melina Rapoport Christine Seah Fernando Pasterán Paola Ceriana Ezequiel Albornoz Alejandra Corso Alejandro Petroni Roberto G Melano

We have characterized nine mcr-1-harboring plasmids from clinical Escherichia coli isolates previously described in Argentina and Canada. Three of these plasmids carried a mcr-1-variant called here mcr-1.5. All these E. coli isolates were not clonally related and were recovered in different years and locations. However, their mcr-1-harboring plasmids showed high identity among them and to other...

Journal: :Antimicrobial agents and chemotherapy 2012
Lucía Fernández Håvard Jenssen Manjeet Bains Irith Wiegand W James Gooderham Robert E W Hancock

Cationic antimicrobial peptides pass across the outer membrane by interacting with negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization in a process termed self-promoted uptake. Resistance can be mediated by the addition of positively charged arabinosamine through the action of the arnBCADTEF operon. We recently described a series of two-component regulators t...

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