Mesoporous MCM-41 silicas anchored with sulfonic acid (–SO3H) groups (denoted MSN-SA) via postsynthesis modification are very effective for the Beckman rearrangement. A simple and convenient procedure for conversion of a variety oximes to their corresponding amides and lactams has been developed. The reaction was carried out in the presence of MSN-SA as the catalyst. The best results for conver...

In a former publication 1 I have shown that the two types of cells which especially act as phagocytes, namely the polynuclear leucocytes with fine granulation and the large mononuclear phagocyte or macrophage of Metschnikoff, are each characterized by a distinct proteolytic enzyme. That enzyme which is contained in the polynuclear leucocytes and as I have previously shown 2 is manufactured in t...

BACKGROUND There is a continuing need for non-aluminium and non-calcium-containing oral phosphate binders. A novel product, i.e. stabilized polynuclear iron hydroxide, has experimentally been shown to be an effective phosphate binder. The purpose of the study was to test the efficacy and tolerability of the compound in hyperphosphataemic patients with stable preterminal renal failure. METHODS...

Abstract We introduce and study a one parameter deformation of the polynuclear growth (PNG) in (1+1)-dimensions, which we call $t$-PNG model. It is defined by requiring that, when two expanding islands merge, with probability $t$ they sprout another island on top merging location. At $t=0$, this becomes standard (non-deformed) PNG model droplet geometry, can be reformulated through longest incr...

The proton affinities of a series of monoand polynuclear zinc-thiolate compounds, mimicking zing finger protein and metallothioneins sites, have been investigated by Density Functional Theory calculations. This allows to evaluate the intrinsic nucleophilicity of synthetic and natural zinc-bound thiolates and to compare their relative reactivities. The site specificity of the experimental thiola...