BACKGROUND Nocturnal enuresis is uncommon in older adults. The paucity of literature about this problem prompts us to review our cases to determine the management strategy. METHODS Six older adults, including 2 females and 4 males, were evaluated for refractory nocturnal enuresis. Only 2 of them had minor daytime urge symptom. Most of them had failed in the treatment using anticholinergics an...

The purpose of this study was to evaluate whether hypercalcemia is associated with downregulation of renal aquaporins (AQPs), including AQP1, AQP2, phosphorylated AQP2 (p-AQP2), AQP3, and AQP4, and if this is the case, to test whether cAMP-phosphodiesterase (PDE) inhibitor treatment can prevent AQP downregulation and prevent the development of polyuria. Vitamin D-induced hypercalcemia in rats w...

Abstract
 Diabetes insipidus is a poluuria polydipsia syndrome with hyperexcretion of hypotonic urine. It still rare in the world. Generally, diagnosed by dehydration and vasopressin test. was reported that woman experienced recurrent hypokalemia, cause unknown. After examination collected urine plasma osmolarity, it found diabetes waspresent. A test performed using intranasal desmopressin...

Craniopharyngioma is an embryonic malformation in the sella and parasella areas. has high survival rate, although patient's quality of life often compromised due to tumor’s location near important anatomical structures such as optic nerve, chiasm, hypothalamic-pituitary axis. tumor resection can provoke diabetes insipidus. Diabetes insipidus (DI) characterized by polyuria, dehydration hypernatr...