(1) HISTORICAL.-In the fully-developed state, choroideremia presents a characteristic and unmistakable picture of which Fig. 1 and Colour Plate 1(a and b) may be taken as examples. The almost total lack of choroidal vessels strongly suggests a developmental anomaly. In fact most of the early writers on, the subject, such as Mauthner (1872) and Koenig (1874), stressed the likeness to choroidal c...

IN the present article an account is given of a skin disease with ocular manifestations. At the beginning the skin disease was diagnosed as lentigenes and the eye-affection was suggested to be a melanoma bulbi. Observation of the clinical picture, however, and later familial investigations, gave clear evidence of a close connection between the two affections, and the condition became recognised...

We report the case of a 67 year old male who presented with a nine year history of a gastric ulcer with symptoms of hematemesis and melena. Histological analysis identified fibrotic lesions and the accumulation of immunoglobulin G4-positive plasma cells with no evidence of malignancy. The lesion extended into the pancreas, where histological lesions and gastric lesions were also observed. This ...

Research has focused most on temperament dimensions of self-regulation or effortful control, general positive emotional reactivity, general negative emotional reactivity, and more specific aspects of negative emotionality reflecting fearfulness and inhibition on the one hand, and anger and irritability on the other hand. Much research has also considered whether temperament dimensions predict s...

Although Louisa May Alcott’s An Old-Fashioned Girl (1869) promotes conventional gender expectations and traditional values, at the same time it depicts heterosexual marriage as mercenary dispassionate. It proposes women’s choice to become self-sustaining a positive alternative marriage. Thus, narrative seems destabilize conventionality promotes: “spinsterhood,” independent career women, same-ge...