Schizotypy provides a useful construct for understanding the development of schizophrenia spectrum disorders. As research on the epidemiology of psychotic symptoms and clinical risk for psychosis has expanded, conceptual challenges have emerged to comprehend the nature and borders of the space comprised between personality variation and psychosis. Schizotypy is considered in light of these more...

In this study, we investigated the Five-factor model in the concurrent prediction of positive symptom schizotypy as measured by the Magical Ideation (Eckblad & Chapman, 1983) and Perceptual Aberration (Chapman, Chapman, & Raulin, 1978) scales and negative symptom schizotypy as measured by the Physical Anhedonia (Chapman, Chapman, & Raulin, 1976) and Revised Social Anhedonia (Eckblad, Chapman, C...

Premonition is a feeling that something is about to happen when no normal information is available, and in which the target cannot be deduced from normally known data in the present. The main aim was to estimate the proportion of people who claim to have had various kinds of premonition experiences, and to explore any association between these experiences and personality variables such as neuro...

Schizotypal personality features and certain neurocognitive deficits have been shown to aggregate in the relatives of schizophrenic patients, supporting the view that both are likely to reflect genetic contributions to liability to schizophrenia. Within the relatives of schizophrenic patients, however, the interrelationships between these potential indicators of liability to schizophrenia are n...

In 2003, Gottesman and Gould advocated using the endophenotype concept in psychiatry genetics; describing it as a measurable component “along the pathway between disease and distal genotype” (p. 636). Especially in schizophrenia research, the idea of endophenotypes has gathered a wide following. Meehl’s definition of schizotaxia [Ref. (1), p. 829], as “an ‘integrative neural defect’ as the only...

Preliminary evidence suggests that theory of mind and empathy relate differentially to factors of schizotypy. The current study assessed 686 undergraduate students and used structural equation modeling to examine links between a four-factor model of schizotypy with performance on measures of theory of mind (Reading the Mind in the Eyes Test [MIE]) and empathy (Interpersonal Reactivity Index [IR...

............................................................................ ii Acknowledgements.............................................................. iv Table of contents................................................................. vi Index of tables..................................................................... xi Index of figures................................................

BACKGROUND SPEM dysfunction is a well-known phenomenon in schizophrenia. The principal aim of the present study was to examine whether SPEM dysfunction is already observable in subjects scoring high on a specific measure of schizotypy (SSQ General Schizotypy) that was selected because of its intimate relationship with schizophrenic prodromal unfolding. METHODS Applying ANOVAs, we determined t...

Genetic variability within the ZNF804A gene has been recently found to be associated with schizophrenia and bipolar disorder, although the pathways by which this gene may confer risk remain largely unknown. We set out to investigate whether common ZNF804A variants affect psychosis-related intermediate phenotypes such as cognitive performance dependent on prefrontal and frontotemporal brain func...

This article introduces and reviews the history of the construct of schizotypy for the special section appearing in the journal. Schizotypy offers a useful construct for understanding the etiology, development, and expression of schizophrenia-spectrum psychopathology and a unifying construct for linking a broad continuum of clinical and subclinical manifestations. The article reviews the descri...