Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction are extensively used to reveal structural information on macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron microscopes automatically acquire thousands of high-quality micrographs. Particles are detected on and boxed out from each micrograph using fully- or semi-automate...

introduction: many studies have been performed to evaluate the stress distribution around endodontic posts; those which compared posts composed of different materials are rare. the aim of this study was to compare stresses induced in dentin by three structurally different posts using photoelasticity method. materials and methods: nine blocks of psm-5 photoelastic material with 45×45×10 mm dimen...

Most dialog systems explicitly confirm user-provided task-relevant concepts. User responses to these system confirmations (e.g. corrections, topic changes) may be misrecognized because they contain unrequested task-related concepts. In this paper, we propose a concept-specific language model adaptation strategy where the language model (LM) is adapted to the concept type(s) actually present in ...

PURPOSE Visual search measures have been used to evaluate the effects of pattern-related visual stress (PRVS), and its alleviation by colored filters, but tasks and results have varied between studies. Performance on a high-difficulty search task was measured in individuals having low- and high-PRVS susceptibility. METHODS Two PRVS groups (low and high) were formed on the basis of participant...

Beyond issues of MTBI etiology, a key question remains the characterization and early identification of those individuals at risk of poor functional outcome. Using a retrospective analysis, the current study aimed at identifying the specific indicators related to return to work in adults with both symptomatic MTBI and functional impacts, having completed a specialized intervention program. In t...

People can reliably distinguish the sex of faces across age groups. Rates of accuracy are lower for infants, however, likely because they lack the pronounced sexually dimorphic features that develop during puberty. Given that previous research has shown that perceivers categorize adult sex automatically, we wondered whether this would extend to the faces of infants for whom sex is less legible....

Ubiquitination is a post-translational modification of proteins involved in a variety of cellular processes. Ubiquitination requires the sequential action of three enzymes: E1 (ubiquitin-activating enzymes), E2 (ubiquitin-conjugating enzymes), and E3 (ubiquitin ligases). This SnapShot highlights the main types of E3 ubiquitin ligases, which can be classified in three families depending on the p...

BACKGROUND Safety climate and occupational stress are related with occupational accident. The present study tried to identify the differences in safety climate and occupational stress according to occupational accidents experience and employment type (e.g., direct workers and subcontract workers). METHODS In this study, we conducted a survey using safety climate scale and Korean Occupational ...

BACKGROUND A limitation of traditional outcome studies from behavioral interventions is the lack of attention given to evaluating the influence of moderating variables. This study examined possible moderation effect of baseline activity levels on physical activity change as a result of the Ready for Recess intervention. METHODS Ready for Recess (August 2009-September 2010) was a controlled tr...

Relatively little is known about the course of PTSD symptoms over time following trauma exposure. Accordingly, this study utilized a specialized structural equation modeling approach, growth mixture modeling, to examine the trajectory of PTSD symptoms across three time points in a sample of Gulf War veterans (n at Time 1 = 2,949, n at Time 2 = 2,313, and n at Time 3 = 1,327). Results were most ...