Osteoporosis is a condition characterized by low bone mineral density (BMD) and micro-architectural changes in the bone tissue. The risk of osteoporosis is partly determined by genetic factors. The role of C677T polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene has been investigated in postmenopausal osteoporosis. However, the relationship between MTHFR polymorphism and BMD is st...

Purpose: Certain changes occur in corneal tissue in women after menopause due to hormonal effects. Purpose of this study is to find out whether postmenopausal women have thinner central corneal thickness (CCT) when compared women of reproductive age group. Measurement of CCT is important for the success of refractive surgeries and for the calculation of intra ocular pressure. Methods: Central c...

Aim of the study To evaluate the differences in the What's My M3 test between pre and postmenopausal women. Material and methods Pre- and postmenopausal women who attended an endocrine gynaecology consultation were studied. In all them, the What's My M3? test was applied. Descriptive statistics, central tendency and dispersion measures were used. Differences between groups were assessed with ...

BACKGROUND Advanced oxidation protein products (AOPPs) are acknowledged as a novel marker of oxidation-mediated protein damage. This study aimed to investigate the plasma levels of AOPPs in postmenopausal osteoporotic women, and to determine the relationship between AOPPs accumulation and lumbar bone mineral destiny (BMD) or bone turnover markers. MATERIAL AND METHODS Lumbar BMD was measured ...

BACKGROUND AND PURPOSE Hemodynamic factors seem to play an important role in the pathogenesis of cerebral ischemic events. The aim of this study was to evaluate whether changes in cerebrovascular reactivity occur in women after menopause. METHODS Using transcranial Doppler ultrasonography, we studied the changes of flow velocity after hypercapnia in the middle cerebral arteries of 45 healthy ...

Data from the National Health Interview Survey, 2015. Among those aged 40-59, perimenopausal women (56.0%) were more likely than postmenopausal (40.5%) and premenopausal (32.5%) women to sleep less than 7 hours, on average, in a 24-hour period. Postmenopausal women aged 40-59 were more likely than premenopausal women aged 40-59 to have trouble falling asleep (27.1% compared with 16.8%, respecti...

Blunting of the normal drop in blood pressure (BP) from day to night is emerging as a strong prognostic indicator of cardiovascular morbidity and mortality. This study evaluated the effects of natural menopause on BP dipping in African American and white women. A total of 112 women (62 premenopausal and 50 postmenopausal) took part in the study. Pre- and postmenopausal groups were comparable in...

OBJECTIVE We observed that estrogen did not show cardioprotective benefits in type 2 diabetic postmenopausal women. We hypothesized that hypertensive and/or overweight women may be less likely to realize cardiovascular benefits from estrogen. METHODS AND RESULTS We administered micronized progesterone (MP) 100 mg or medroxyprogesterone acetate (MPA) 2.5 mg with conjugated equine estrogen (CEE...

Age Related Changes in Indices of Bone Metabolism and Oxidative Stress Postmenopausal Women Southern Nigeria

Deficiency of endogenous estrogens has been associated with a higher incidence of coronary heart disease (CHD) in women. We investigated whether natural menopause is associated with reduced protection from postprandial lipemia, which represents a risk indicator of CHD. Twenty-three postmenopausal women (mean age, 50+/-1 [SD] years; body mass index, 24.6+/-2.8 kg/m(2)) and 21 premenopausal women...