Objective: Indomethacin is a non-selective cyclooxygenase (COX) inhibitor that is commonly administered to extremely low gestational age neonates for symptomatic patent ductus arteriosus. It suppresses prostaglandins which modulate growth and secretion of various hormones. We examined the hypothesis that early postnatal administration of Indomethacin may influence growth and development of test...

Pulmonary tumors were induced in mice that were suckled by mothers that received urethan during lactation. More induced tumors appeared in sucklings when urethan was injected into lactating mothers soon after delivery. When pregnant mice were treated with urethan during gestation and lactation their offspring had a significantly increased incidence of pulmonary tumors, and the number of tumors ...

According to some studies, the number of addicted females in reproductive ages has been increased. The present study was designed to investigate the effect of oral morphine consumption on the development of CNS and body growth in rats. For this purpose, female Sprauge-Dawley rats were divided into control and experimental groups (20 animals in each group). Maintenance dose of morphine (0/4 mg/m...

BACKGROUND Postpartum depression (PPD) is a neglected area of maternal health care in developing countries like Nepal; not only in the treatment aspect, but also, in the areas of research. However, it is important to identify and treat postpartum depression because it can have grave consequences for both the mother and her children. OBJECTIVE To determine the screening prevalence and risk fac...

Pulmonary tumors were induced in mice that were suckled by mothers that received urethan during lactation. More induced tumors appeared in sucklings when urethan was injected into lactating mothers soon after delivery. When pregnant mice were treated with urethan during gestation and lactation their offspring had a significantly increased incidence of pulmonary tumors, and the number of tumors ...

A variety of neoplasms can develop in each fetal organ. Most fetal neoplasms can be detected by careful prenatal ultrasonographic examination. Some neoplasms show specific ultrasonographic findings suggesting the differential diagnosis, but others do not. Knowledge of the presence of a neoplasm in the fetus may alter the prenatal management of a pregnancy and the mode of delivery, and facilitat...

Doppler ultrasound was used to measure left renal artery blood flow velocity and pulsatility index on the first, third, and seventh day of postnatal life in 18 very low birthweight small for gestational age (SGA) infants. The values were compared with those from 18 weight matched and 18 gestation matched controls. SGA infants had significantly lower blood flow velocity than their gestation matc...

Background The postnatal period represents a vulnerable phase for mothers and newborns where both face increased risk of morbidity and death. WHO recommends postnatal care (PNC) for mothers and newborns to include a first contact within 24 hours following the birth of the child. However, measuring coverage of PNC in household surveys has been variable over time. The two largest household survey...

Congenital diaphragmatic hernia (CDH) is a rare condition. The reported incidence of intrathoracic renal ectopia due to CDH is also rare. A right-sided thoracic kidney is much less common due to the location of the liver. Isolated intrathoracic kidney is usually asymptomatic and diagnosed incidentally on chest imaging. The authors report on a 21days old female infant with late-presenting right ...

PURPOSE Higher long-chain polyunsaturated fatty acids (LCP) in infant compared with maternal lipids at delivery is named biomagnification. The decline of infant and maternal docosahexaenoic acid (DHA) status during lactation in Western countries suggests maternal depletion. We investigated whether biomagnification persists at lifelong high fish intakes and whether the latter prevents a postpart...