BACKGROUND As a drug originally introduced for its anticonvulsant effects, gabapentin has been recently shown to be effective in the treatment of nausea and vomiting in various clinical settings. This study compared the antiemetic efficacy of oral gabapentin, intravenous ramosetron and gabapentin plus ramosetron in patients receiving fentanyl-based patient-controlled analgesia after laparoscopi...

BACKGROUND AND OBJECTIVES Postoperative nausea and vomiting (PONV) is frequent and potentially a severe complication that increases the length of anesthetic recovery and causes patient dissatisfaction. The evaluation of the risk of PONV and institution of prophylactic measures aiming the well-being of patients and cost reduction are frequent in the medical literature. This observational study e...

STUDY OBJECTIVE To investigate whether betamethasone decreases the incidence of postoperative nausea/vomiting (PONV) and reduces postoperative pain following partial mastectomy. DESIGN Prospective randomized, double-blinded study. SETTING Operating room and Postanesthesia Care Unit of a university hospital. PATIENTS 80 ASA physical status 1 and 2 women scheduled for elective breast cancer...

STUDY OBJECTIVE To investigate whether the phase of menstrual cycle influences the incidence of postoperative nausea and vomiting (PONV) in women undergoing general anesthesia for elective laparoscopic gynecological surgery. DESIGN Prospective, observational, blinded study. SETTING General hospital, Postanesthesia Care Unit, and gynecologic floor room. PATIENTS 111 ASA physical status 1 a...

OBJECTIVE: Postoperative nausea and vomiting (PONV) is a common complication in patients after middle ear surgeries conducted under general anaesthesia. This prospective, randomized, double blind study study compares the effects of anti emetic drugs palonosetron and ondansetron on postoperative nausea and vomiting in patients undergoing middle ear surgeries under general anaesthesia. METHOD: Si...

Previous randomized controlled trials have reported conflicting findings on the superiority of palonosetron over ramosetron for preventing postoperative nausea and vomiting (PONV). Therefore, the present systematic review was registered in PROSPERO (CRD42016038120) and performed to compare the efficacy of perioperative administration of palonosetron to that of ramosetron for preventing PONV. We...

BACKGROUND Few studies have investigated the use of dexmedetomidine in patients with a high risk of postoperative nausea and vomiting (PONV) following gynaecological laparoscopic surgery. OBJECTIVE To investigate if the intra-operative use of dexmedetomidine could reduce the incidence of PONV in this patient population. DESIGN A randomised, double-blind, placebo-controlled trial. SETTING ...

introduction: controversy remains as to the advantages and disadvantages of pharyngeal packing during septorhinoplasty. our study investigated the effect of pharyngeal packing on postoperative nausea and vomiting and sore throat following this type of surgery or septorhinoplasty.   materials and methods: this clinical trial was performed on 90 american society of anesthesiologists (asa) i or ii...

BACKGROUND Postoperative nausea and vomiting (PONV) is commonly seen after laparoscopic surgery. In this randomized double blind prospective clinical study, we investigated and compared the efficacy of palonosetron and granisetron to prevent postoperative nausea and vomiting after laparoscopic cholecystectomy. PATIENTS #ENTITYSTARTX00026; METHODS Sixty female patients (18-65 yrs of age) under...