Increasing crop production at a time of rapid climate change represents the greatest challenge facing contemporary agricultural research. Our understanding of the genetic control of yield derives from controlled field experiments designed to minimize environmental variance. In spite of these efforts there is substantial residual variability among plants attributable to Genotype × Environment in...

1. The principle of the N I H test is the immunisation of mice with different vaccine concentrations, followed by challenge infection with one virus concentration of 5 to 50 LD50/dose of the challenge virus strain (CVS) derived from the Pasteur strain. The protection rates ( E D 5 0 ) of a standard and the test vaccines are calculated, and the potency of the test vaccine is given in Internation...

Four different nitroimidazole derivatives, with up to two iodine atoms on the imidazole ring, were investigated for their radiosensitizing potency under hypoxic conditions, in order to test whether the introduction of iodine atoms increases the radiosensitizing potency of nitroimidazoles. Misonidazole and metronidazole were used as controls. Human colonic adenocarcinoma cells were incubated wit...

thimerosal, which is approximately 50% mercury by weight is a preservative widely used in vaccines since the 1930’s. it meets the requirements for a preservative as set forth by pharmacopeia challenge test and has been shown to be effective against a broad spectrum of pathogens. in july 1999, the public health service agencies and vaccine manufacturers agreed that thimerosal should be reduced o...

Three potential reactivators of nerve agents-inhibited acetylcholinesterase: 2-[(hydroxyimino)phenylmethyl]-1-methylpyridinium iodide 3a, 2-[(hydroxyimino)pyridin-2ylmethyl]-1-methylpyridinium iodide 3b and 2-[(1-hydroxyimino) ethyl]-1-methylpyridinium iodide 3c were synthesized. Their reactivation potency was examined using a standard in vitro reactivation test. A rat brain homogenate was used...

The hexanolic extract of Dennellia tripetala was tested for acute toxicity on 3 Instar larvae of Aedes aegypti reared in the Laboratory at the Department of Zoology, University of Ibadan,. Six sets of graded concentrations 30pprn, 50ppm 60pprn 70pprn, 80ppm and 90ppm were tested for acute toxicity on the 3 instar larvae of Aedes agypti and total percentage mortalities recorded at intervals of 1...

Bacillus thuringiensis var. israelensis and Bacillus sphaericus products were assayed against their respective reference powders IPS82 and SPH88. Since their production in 1982 and 1988, the potency and larvicidal activity of these standard powders have been regularly checked on their test insects Aedes aegypti (for IPS82) or Culex pipiens (for SPH88). Over the 16-year evaluation period of IPS8...