background: narcotic addiction is one of the most important problems in human communities that unfortunately it's prevalence has been increased in our country inconveniently. opium has various effects on the parts of body. many studies has been performed about these effects, but opium effect on common bile duct has allocated only small quantity. materials and methods: this study is a cross-sect...

bile duct ligation (bdl) is shown to induce cholestasis-related liver function impairments as well as consequent cognitive dysfunctions (i.e. impaired learning and memory formation). this study investigates the effects of cholestasis (14, 21 and 28 days post bile duct ligation) on spatial and non-spatial novelty detection, using a non-associative task. male mice weighing 30-35 g were used. chol...

Two-dimensional numerical analysis is conducted to determine the influence of upstream surface modifications a novel clerestory shaped rib turbulator on thermal performance augmentation. The divided into two parts where upper always normal incoming flow and lower surface, which inclined flow. elevation vertical varied using non-dimensional approach length (h/e=0, 0.25, 0.5 0.75), inclination an...

Numerical study of heat transfer and fluid flow over vertical double forward facing step were presented. The k-w model with finite volume method was employed to solve continuity, momentum, and energy equations. Different step heights were adopted for range of Reynolds number varied from 10000 to 40000, and range of temperature varied from 310K to 340 K. The straight side of duct is insulated wh...

Pancreas injury by partial duct ligation (PDL) activates beta cell differentiation and proliferation in adult mouse pancreas but remains controversial regarding the anticipated increase in beta cell volume. Several reports unable to show beta cell volume augmentation in PDL pancreas used automated digital image analysis software. We hypothesized that fully automatic beta cell morphometry withou...

The large animal model with benign biliary stricture (BBS) is essential to undergo experiment on developing new devices and endoscopic treatment. This study conducted to establish a clinically relevant porcine BBS model by means of endobiliary radiofrequency ablation (RFA). Endoscopic retrograde cholangiography (ERC) was performed on 12 swine. The animals were allocated to three groups (60, 80,...