Chronic alcohol ingestion is known to increase the generation of reactive oxygen species (ROS), thereby leading to liver damage. Antioxidant enzymes act individually or in combination to reduce or counter the effect of these ROS. Chronic administration of alcohol at (40% v/v, 1 ml/100 g), for 6 weeks showed a significant (p<0.05) elevated levels of alanine aminotransferase (ALT), aspartate amin...

UNLABELLED The pathogenesis of hepatic encephalopathy is multifactorial, involving gut-derived toxins such as ammonia, which has been demonstrated to induce oxidative stress. Therefore, a primary hepatic encephalopathy treatment target is reducing ammonia production in the gastrointestinal tract. AST-120, an oral adsorbent of engineered activated carbon microspheres with surface areas exceeding...

Objective: The present study was aimed at investigating the hepatoprotective and antioxidant activity of the methanolic extract of Monochoria vaginalis (MEMV) against Carbontetra chloride (CCl4) induced acute liver injury in rats in preventive models. Methods: Toxic control, methanolic extract and standard drug Silymarin treated rats were received a single dose of CCl4 (150 μl/100 g, 1:1 in gro...

Radiation-induced liver toxicity is a major limitation to the use of radiation in the treatment of intrahepatic cancers. The purpose of this study was to evaluate the potential radioprotective effect of a smallmolecule tumor necrosis factor alpha (TNF-) inhibitor, UTL-5g, against radiation-induced acute liver injury. Mice were pre-treated by i.p. injection with UTL-5g and control vehicle one h...

A $\ast$-ring&#x0D; $R$ is called a $\pi$-Baer $\ast$-ring, if for any projection invariant left ideal $Y$ of $R$, the right annihilator $Y $&#x0D; generated, as ideal, by projection.&#x0D; In this note, we&#x0D; study some properties such $\ast$-rings.&#x0D; We indicate interrelationships between $\ast$-rings and related classes rings as&#x0D; rings, Baer $\ast$-rings, quasi-Baer $\ast$-rings....

Acute suppurative thyroiditis (AST) is a rare condition, as the thyroid gland is relatively resistant to infection. Thyroid function tests are usually normal in AST. A few cases of AST associated with thyrotoxicosis have been reported in adults. We report a case of AST that was associated with thyrotoxicosis in a 70-year-old woman. We diagnosed AST with thyroid ultrasonography and fine needle a...

BACKGROUND Acid suppression therapy (AST) is routinely used in critically ill patients to prevent stress-related mucosal bleeding (SRMB). OBJECTIVE Our objective was to determine the impact of a structured educational intervention on AST used for prevention of SRMB on appropriateness of AST. METHODS A single-center, retrospective, cohort study of appropriate use of AST in critically ill pat...

Acute liver failure (ALF) remains an extremely poor prognosis and high mortality; with no effective treatments. The endotoxin tolerance (ET) phenotype has been reported to exhibit protective activities in several sepsis models. We now investigated the effects and underlying intraperitoneal injection of the same volume of pyrogen-free 0.9% sodium chloride instead of LPS for five consecutive days...