OBJECTIVES: Low levels of pregnancy-associated plasma protein-A in pregnant women linked to unhealthy placentation and a spectrum maternal fetal complications. Its assessment as single biomarker has the potential identify high-risk pregnancies. This prospective observational study was conducted find correlation between low first trimester pregnancy with various obstetric outcomes establish if i...

Introduction In pregnancy, vitamin D deficiency is associated with increased risk of fetal growth restriction and preeclampsia. The underlying mechanisms are not known, but placental dysfunction believed to play a role. Danish population, where health authorities recommend 10 µg/day supplement during we explored current use supplements status. term placentas, alterations in metabolism growth, e...

we encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. this child was being fed with a low-protein diet when the skin disorder developed. a deficiency in plasma levels isoleucine, was confirmed. supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. we assume that in our patient the sk...

context: normal pregnancy is associated with sodium and water retention, which results in plasma volume expansion prior to placental implantation. the explanation offered for these events is that pregnancy ‘resets’ both volume and osmoreceptors. evidence acquisition: the mechanisms for such an enigmatic ‘resetting’ in pregnancy have not previously been explained. however, recent human pregnancy...