The molecular mechanisms that maintain quiescence of the myometrium throughout most of pregnancy and promote its transformation to a highly coordinated contractile unit culminating in labor are complex and intertwined. During pregnancy, progesterone (P4) produced by the placenta and/or ovary serves a dominant role in maintaining myometrial quiescence by blocking proinflammatory response pathway...

background: embryo transfer has received little clinical attention and has been the most inefficient step in in-vitro fertilization (ivf). recent reports have suggested that an awareness of the position and length of the uterus during embryo transfer might be helpful in improving pregnancy rate. objectives: the main objective of the present study was to determine the relation between the length...

Abstract Objectives: to estimate the prevalence of perceived stress and verify associated factors in pregnant women assisted by Family Health teams Montes Claros, Minas Gerais - Brazil. Methods: epidemiological, cross-sectional, analytical study, nested a population-based cohort. Sociodemographic obstetric characteristics physical mental health conditions were assessed. The level was estimated ...

OBJECTIVES To measure the prevalence and risk factors associated with iron supplementation among pregnant women in the municipality of Rio Grande, Southern Brazil. METHODS All mothers living in this municipality who had children in 2007 were surveyed for demographic, socioeconomic and health care received during pregnancy and childbirth. The statistical analysis consisted of Poisson regressio...

Parity is associated with a short-term increase in breast cancer (BC) risk followed by a long-term decrease in risk. BC diagnosed 5-7 years after a completed pregnancy is associated with worse outcomes. BC is not a single disease. The dual effect of pregnancy could account for the BC characteristics at presentation (i.e. younger age and more advanced disease) and worse outcomes observed among H...

INTRODUCTION In women showing impaired fertility, a decreased response to ovarian stimulation is a major problem, limiting the number of oocytes to be used for assisted reproduction techniques (ART). Despite the several definitions of poor response, it is still a matter of debate whether young poor responder patients also show a decrease in oocyte quality. The objective in this study was to inv...

©FSRH J Fam Plann Reprod Health Care 2010: 36(2) Introduction The sex steroid progesterone plays a major role in the regulation of female reproductive activity. Circulating levels of progesterone are maximal in the secretory phase of the menstrual cycle, its main source being the corpus luteum. The effects of progesterone are mediated via the progesterone receptor (PR), which is essential not o...

The implantation of trophoblast cells at extrauterine sites still results in decidualization. The objective of the present study was to compare decidualization at eutopic and ectopic implantation sites. Tissues from women undergoing elective termination of uterine pregnancy and from women with ectopic pregnancy were used to detect the presence of cells important for the maintenance of pregnancy...

Feeding pregnant rats a protein-restricted (PR) diet induces altered expression of candidate genes in the liver of the adult offspring, which can be prevented by supplementation of the PR diet with folic acid (PRF). We investigated the effect of maternal nutrition during pregnancy on the liver transcriptome in their adult male offspring. Pregnant rats were fed control, PR or PRF diets. Male off...

We have previously demonstrated that maternal protein restriction during pregnancy leads to raised blood pressure and endothelial dysfunction in the offspring (F1). Here we show that these characteristics are transmitted to the F2 offspring through the maternal line, in the absence of any additional challenges to the F1. Female Wistar rats were fed either a control (18% casein) or protein-restr...