Recently, assisted reproductive techniques have been used to prevent further miscarriages in women with recurrent miscarriage. One approach uses either screening or diagnosis of embryonic chromosomes prior to embryo replacement [preimplantation genetic screening (PGS)/preimplantation genetic diagnosis (PGD)]. The second approach involves surrogacy. However, PGS/PGD assumes that the embryo is ch...

Many published papers suggest a favourable impact of preimplantation genetic screening (PGS) on implantation and pregnancy rates, but more recent randomized studies have not confirmed, or could not conclude, that PGS actually improved implantation rates. Team inexperience in embryo screening has been mentioned as the origin of the discrepancies; thus some clinicians allege a need for more power...

Background: During the last half of the twentieth century, there were a series of advancements in reproductive medicine and genetic testing. Preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) are the two main methods of preconception genetic testing. The purpose of this article is to present the existing literature regarding the patients’ attitudes towards PGD a...

The researchers described the linear amplification via transposon insertion (LIANTI) method today in Science, reporting that it enables micro-copy number variation detection with kilobase resolution. Sunney Xie, senior author on the study, said that he is interested in using the method for preimplantation genetic screening and diagnosis, which typically rely on the analysis of single or very fe...

The purpose of prenatal diagnosis tests is insisting of diagnosis of neonatal disorders, preparing a range of informed choices and making couples at risk to be ready for having children with genetic disorders as well. The aim of this article is to investigate all of the tests in order to determine the best one which has the lowest risk and the highest sensitivity. Screening tests (maternal bloo...