Background. Protecting healthcare workers (HCWs) from COVID-19 is a global priority. Anova Health Institute (Anova) the PEPFAR (US President’s Emergency Plan for AIDS Relief) District Support Partner Johannesburg, Cape Town, Sedibeng, Capricorn and Mopani districts in South Africa, operating public sector primary facilities. At time of emergence COVID-19, employed close to 4 000 people: 41% com...

The United Nations (UN) Millennium Development Goals (MDGs) expire in 2015. A high-level panel, appointed to discuss the global development agenda post-2015, reported back in May 2013 with its recommendations. These are likely to prove extremely important for determining the global health budget over the coming decade. Who the ‘‘winners’’— those who will benefit from UN endorsement and enhanced...

In January 2003, United States President George W. Bush announced the President’s Emergency Plan for AIDS Relief (PEPFAR), the appropriation of $15 billion dollars for programs to combat the global HIV/AIDS epidemic, in his State of the Union address. Congress responded with the legislative authorization for the plan, the United States Leadership Against Global HIV/ AIDS, Tuberculosis, and Mala...

The provision of antiretroviral treatment (ART) has decreased morbidity and mortality in people living with HIV/AIDS [1,2]. However, introducing ART to subSaharan Africa was a topic of hot debate just a few years ago. Concerns about adherence and subsequent development of drug resistance, poor infrastructure, logistic and human capacity, and cost-effectiveness were the major issues [3]. Once pi...

BACKGROUND Governments and international donors have partnered to provide free HIV treatment to over 6 million individuals in low and middle-income countries. Understanding the determinants of HIV treatment costs will help improve efficiency and provide greater certainty about future resource needs. METHODS AND FINDINGS We collected data on HIV treatment costs from 54 clinical sites in Botswa...

BACKGROUND/AIMS Sickle cell disease (SCD) is a life-threatening, autosomal recessive blood disorder prevalent in sub-Saharan Africa. We identified the prevalence of sickle cell trait (SCT) among pregnant women and their male partners in Enugu State, Nigeria, and determined the accuracy of self-reported sickle cell status and its reliability for identifying high-risk newborns for targeted screen...

BACKGROUND Little information exists on the technical assistance needs of local indigenous organizations charged with managing HIV care and treatment programs funded by the US President's Emergency Plan for AIDS Relief (PEPFAR). This paper describes the methods used to adapt the Primary Care Assessment Tool (PCAT) framework, which has successfully strengthened HIV primary care services in the U...

INTRODUCTION People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The United States (US) President's Emergency Plan for AIDS Relief (PEPFAR) is com...

Nigeria was part of an HIV epidemic that once threatened to engulf all of West Africa. The trajectory was altered by the interventions of international donor agencies such as the US President’s Emergency Plan for AIDS Relief (PEPFAR), local organizations, and other agencies who assisted in reducing the threat. Birth Attendants provide an important resource for Prevention of Mother-to-Child Tran...