Maternal immune tolerance of the semiallogeneic fetus is a complex phenomenon. Macrophages are an abundant cell population in the human decidua, and changes in distribution or phenotype may be involved in the development of preeclampsia. The aim of this study was to assess the distribution and phenotype of macrophages in preterm preeclamptic, preterm control, and term control placentas. Placent...

BACKGROUND To determine whether patients with placenta previa who delivered preterm have an increased risk for recurrent spontaneous preterm birth. METHODS This retrospective population based cohort study included patients who delivered after a primary cesarean section (n = 9983). The rate of placenta previa, its recurrence, and the risk for recurrent preterm birth were determined. RESULTS ...

In preterm and term infants, brainstem and middle latency auditory evoked responses (ABR and MLR) were obtained at 40 and 52 weeks conceptional age (CA) and at 5 years of age. A neurological and neuropsychological evaluation was performed at 5 years of age. To study the effect of preterm birth on the maturation of the ABR and MLR, the preterm infants were divided into early and late preterm gro...

Background: Contents of breast milk may change during the first weeks after childbirth, especially in preterm deliveries. The present study aimed to determine the macronutrient contents of breast milk in the mothers with preterm delivery. Methods: This prospective-descriptive study was conducted in Mahdieh Hospital in Tehran, Iran in 2015. Participants included the mothers with preterm deliver...

BACKGROUND Preterm birth is associated with abnormalities in growth, body composition, and metabolism during childhood, but adult data are scarce and none exist for their offspring. We therefore aimed to examine body composition and cardiovascular risk factors in adults born preterm and their children. METHODS A cohort of 52 adults (aged 35.7 years, 54% female, 31 born preterm) and their term...

Background: Preterm babies have increased risk of morbidity and mortality which is inversely related to both gestational age and birth weight. Most preterm births result from maternal or foetal medical conditions. Objectives: To determine the prevalence and outcome of preterm admissions at the Special Care Baby Unit of the Niger Delta University Teaching Hospital, as well as their morbidity pat...

“Late-preterm birth” refers to babies born between 34 and 36 weeks of pregnancy. During the past decade in the United States, the delivery of late preterm infants has increased by 14%. There are approximately 500,000 preterm births (births before 37 completed weeks of gestation), which account for 12.5% of live births in the United States annually. Of these preterm births, more than 70% (approx...

UNLABELLED Poor postnatal growth after preterm birth does not match the normal rapid growth in utero and is associated with preterm morbidities. Insulin-like growth factor 1 (IGF-1) axis is the major hormonal mediator of growth in utero, and levels of IGF-1 are often very low after preterm birth. We reviewed the role of IGF-1 in foetal development and the corresponding preterm perinatal period ...

BACKGROUND AND OBJECTIVES Preterm children, compared with term children, are at increased risk of emotional and behavioral problems (EB-problems). Prevalences of EB-problems seem to vary with degree of prematurity and age at assessment. We therefore assessed individual stability of EB-problems in preterm compared with term children first before school entry and again 1 year after school entry, ...

OBJECTIVE To investigate time trends in preterm birth in Europe by multiplicity, gestational age, and onset of delivery. DESIGN Analysis of aggregate data from routine sources. SETTING Nineteen European countries. POPULATION Live births in 1996, 2000, 2004, and 2008. METHODS Annual risk ratios of preterm birth in each country were estimated with year as a continuous variable for all bir...