PURPOSE Thyroid dysfunction is common in preterm infants. Congenital hypothyroidism causes neurodevelopmental impairment, which is preventable if properly treated. This study was conducted to describe the characteristics of thyroid dysfunction in very low birth weight infants (VLBWIs), evaluate risk factors of hypothyroidism, and suggest the reassessment of thyroid function with an initially no...

Preterm Birth: Introduction Low birthweight defines neonates who are born too small, and preterm or premature birth are the terms used to define neonates who are born too early. With respect to gestational age, a newborn may be preterm, term, or postterm. With respect to size, a newborn may be normally grown or appropriate for gestational age, small in size or small-for-gestational age, or over...

Stålhammar, M. 2016. Neutrophil Chemotaxis and Respiratory Burst in Term and Preterm Newborn Infants. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1265. 47 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9722-4. Neutrophil activation is the most important initial immune defense against invading microbes in newborn infants. The reduced neutro...

We read with interest Dr. Hutchon's commentary on our recent review entitled " Enhanced Monitoring of the Preterm infant during Stabilization in the Delivery Room " (1). We would like to thank him for his kind comments. He raised a number of important points related to one aspect of our review, namely heart rate acquisition in the delivery room. He was disappointed by our " characterization of ...

The response of the preterm and newborn lung to airborne pathogens, particles, and other insults is initially dependent on innate immune responses since adaptive responses may not fully mature and require weeks for sufficient responses to antigenic stimuli. Foreign material and microbial agents trigger soluble, cell surface, and cytoplasmic receptors that activate signaling cascades that invoke...

In the first case, the AA and glucose were infused through a perinatal port system into the umbilical vein at 30 weeks' gestation due to severe IUGR. The patient received daily hyperbaric oxygenation (HBO, 100% O2 ) with 1.4 atmospheres absolute for 50 min for 7 days. At 31+4  weeks' gestation, the patient gave birth spontaneously to a newborn weighing 1378 g, pH 7.33, APGAR score 4/6/intubatio...

OBJECTIVE Recent studies have shown that from the postconceptional age of 33 weeks, preterm infants are able to memorize tactile information about the shape of an object by using their hands, and can detect differences with another shape. This study aimed to investigate tactile abilities earlier on in development, in very preterm and mildly preterm human infants. METHODS Infants were assigned...

Birthweight significantly influences the health and nutrition of a newborn. Low birth weight (LBW) is global problem in both high low income countries it carries significant morbidity mortality. In Nigeria, Prematurity, has been found to be major cause LBW. The burden managing these patients especially those who are extremely weight(<1000g) high, due lack specialized equipped newborn units, ...

Amplitude-integrated electroencephalogram (aEEG) is a readily available and practical tool for the assessment of time-compressed electroencephalogram (EEG) trend at the bedside. Its interpretation and its learnability are considerably easier compared to those of conventional EEG. For those reasons, aEEG is now a daily part of clinical surveillance for continuous brain function monitoring of cri...

Procalcitonin (PCT) levels are elevated early after birth in newborn infants; however, the physiological features and reference of serum PCT concentrations have not been fully studied in preterm infants. The aims of the current study were to establish an age-specific percentile-based reference curve of serum PCT concentrations in preterm infants and determine the features. The PCT concentration...