OBJECTIVE To explore a risk factor approach for identifying preventive interventions that require more in-depth economic assessment, including cost-effectiveness analyses. METHODS A three-step approach was employed to: (i) identify the risk factors that contribute most substantially to disability-adjusted life years (DALYs); (ii) re-rank these risk factors based on the availability of effecti...

OBJECTIVE To review the main risk factors for ischemic heart disease and preventive strategies during childhood. SOURCES Medline review between 1985 and 2001, and key references from the studies evaluated. CONCLUSIONS Preventive interventions that may start in childhood are described for risk factors such as hyperlipidemias, obesity, smoking and systemic hypertension. Results of early diagn...

an earlier overview of systematic reviews and a subsequent editorial on single-component versus multifaceted interventions to promote knowledge translation (kt) highlight complex issues in implementation science. in this supplemented commentary, further aspects are in focus; we propose examples from (kt) studies probing the issue of single interventions. a main point is that defining what is a ...

Preventive care measures remain underutilized despite recommendations to increase their use. The objective of this review was to examine the characteristics, types, and effects of paper- and computer-based interventions for preventive care measures. The study provides an update to a previous systematic review. We included randomized controlled trials that implemented a physician reminder and me...

This paper proposes growth mixture modeling to assess intervention effects in longitudinal randomized trials. Growth mixture modeling represents unobserved heterogeneity among the subjects using a finite-mixture random effects model. The methodology allows one to examine the impact of an intervention on subgroups characterized by different types of growth trajectories. Such modeling is informat...

Family-focused prevention programs have been shown to effectively reduce a range of negative behavioral health outcomes but have had limited reach. Three key barriers must be overcome to expand the reach of family-focused prevention programs and thereby achieve a significant public health impact. These barriers are (1) current social norms and perceptions of parenting programs; (2) concerns abo...

Cardiovascular diseases are the main cause of death in Argentina. This article analyzes economic evaluations on cardiovascular prevention for this country. A literature search was conducted in five electronic databases during December 2009. Inclusion criteria were complete economic evaluations addressing at least one cardiovascular health outcome for the Argentinean population. Finally, nine st...

Primary health care has the potential to contribute to population health at the individual and population levels. The '5As' (ask, assess, advise/agree, assist and arrange) provide a framework to realise this potential, especially for disadvantaged and vulnerable populations, not only by better organising multidisciplinary preventive interventions within primary health care, but also by linking ...

BACKGROUND Anxiety disorders are highly prevalent in primary care and cause a substantial burden of disease. Screening on risk status, followed by preventive interventions in those at risk may prevent the onset of anxiety disorders, and thereby reduce the disease burden. The willingness to participate in screening and interventions is crucial for the scope of preventive strategies, but unknown....

This study evaluated the efficacy of a computer–based relationship focused preventive intervention (ePREP) relative to a depression and anxiety focused computer–based preventive intervention (CBASP) and a control group. Ninety–one young adults in dating relationships were randomly assigned to one of the three conditions. Assessments were conducted at baseline and at an eight week follow up. Par...