Primary central nervous system lymphoma (PCNSL) is a rare cancer that confined to the brain, spinal cord, leptomeninges and eyes. The origin of this type of lymphoma is often type B lymphocytes, and because the central nervous system (CNS) has no lymph nodes or lymphatic vessels, the cause of PCNSL is still uncertain (1). But its source appears to be from lymphocytes located in the CNS (2). Thi...

Primary testicular lymphoma (PTL) is a rare form of extranodal lymphoma, this neoplasm the most common malignant tumor testis in elderly age, and majority cases are histologically diffuse large B-cell (DLBCL), accounting for 80% to 98% non-hodgkin lymphoma. Patients with primary DLBCL show continuously high risk recurrence no plateau survival curves tendency involve other sites, especially cent...

The authors present the case of a 37-years-old man with pancolic Crohn’s disease (CD) diagnosed 20 years ago, characterized by a penetrating behavior with need for surgery (segmental colon resection) for a colovesical fistula. Due to a corticodependent evolution, the patient has been in treatment with azathioprine for 8 years, with only partial clinical response, reason why he started inflixima...

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Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

Primary cutaneous lymphomas, which are diagnosed with only skin involvement, can be of B or T cell origin. Due to their varied origin as well diverse presentations, these groups have been divided further into more descriptive and representative groups. The subtypes primary marginal zone lymphoma (PCMZL), follicle center (PCFCL), diffuse large lymphoma, leg type (PCDLBCL-LT) intravascular B-cell...