Introduction Cecil Alergant's contributions to the specialty were both unique and extensive. He founded a great tradition in 1967 by inaugurating the first university course which culminated in an examination for a Diploma in Venereology awarded by the University of Liverpool. This remains the only Diploma in the specialty awarded by a university in the United Kingdom. Cecil's loyalty and servi...

Management of cardiac symptoms in myasthenia gravis (MG) patients can be challenging. The aim of this report is to describe the safe use of ivabradine for stable angina in MG patients. A 48 y.o. woman, with MG diagnosis, presented stable angina. Therapies choices were reduced considering concomitant disease as well as previous and unsuccessful cardiologic managements. Ivabradine showed unexpect...

The incidence, severity, morbidity, and mortality of odontogenic infections have declined dramatically over the years. This reduction in mortality was not due to the first use of penicillin in the treatment of these infections. Rather, it was due to application of the principles of the initial establishment of airway security, followed by early and aggressive surgical drainage of all anatomical...

Exercise, ergonovine and the cold pressor test have been used to provoke variant angina attacks. The sensitivity of these three tests was compared in 34 hospitalized patients with well documented, active variant angina who had recently undergone coronary arteriography. The three tests were usually perfornmed on three consecutive days, and 28 of the 34 had the three tests within 1 week. Angina w...

Ludwig's angina can seldom be complicated by necrotizing fasciitis. Due to the rapidly progressing nature of this infection and the potential for airway compromise and death, it is important to be aware of different ways in which this disease process can present in order to recognize and treat it emergently. We report here an unusual presentation of a case of Ludwig's angina complicated by necr...

We present the case of a 46-year-old woman with episodes of chest pain with ST-T segment elevation and paroxysmal high-degree atrioventricular block and syncopal episodes. Coronary angiography revealed no significant atheromatous lesions. The patient was treated with nitrates and calcium channel blockers but syncopal episodes with atrioventricular block persisted. A DDD-R pacemaker was implante...

OBJECTIVE The aim of this study was to investigate whether the Japan Arteriosclerosis Longitudinal Study (JALS) score, which is calculated from the traditional atherosclerotic coronary risk, is associated with the incidence of coronary vasospasms. METHODS We performed vasospasm provocation tests with acetylcholine in 109 patients referred to our hospital due to suspected vasospastic angina an...

Dept of Pharmacology & PharmacoGenomics Research Center, Inje University College of Medicine; Dept of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, Cardiovascular Center & Cardiology Division, Seoul St. Mary’s Hospital & College of Medicine, The Catholic University of Korea, Seoul; Dept of Cardiology, Catholic University Uijeongbu St. Mary’s Hospital, Uijeongbu; Dept of Car...

This study aimed to determine the incidence and the risk factors of hospitalization for variant angina (VA) in Korean patients. Using the National Inpatient Sample (NIS) database, manufactured and released by the Health Insurance Review and Assessment Service (HIRA) in Korea, the incidence of hospitalization and rehospitalization for VA were calculated. The numbers of patients hospitalized for ...