Computer networks lack a general control paradigm, as traditional networks do not provide any networkwide management abstractions. As a result, each new function (such as routing) must provide its own state distribution, element discovery, and failure recovery mechanisms. We believe this lack of a common control platform has significantly hindered the development of flexible, reliable and featu...

BACKGROUND Production of pharmaceuticals in plants provides an alternative for chemical synthesis, fermentation or natural sources. Nicotiana benthamiana is deployed at commercial scale for production of therapeutic proteins. Here the potential of this plant is explored for rapid production of precursors of artemisinin, a sesquiterpenoid compound that is used for malaria treatment. METHODOLOG...

This article aims to show the problem of Overall Equipment Effectiveness (OEE) monitoring and performance measurement on a case study done in a small company. Losses occur during the production process and the ways of detecting them must be analyzed. The methodology for calculating total Overall Equipment Effectiveness is followed while applying monitoring tools. Some existing methods used for ...

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The secondary metabolites of higher plants include diverse chemicals, such as alkaloids, isoprenoids and phenolic compounds (phenylpropanoids and flavonoids). Although these compounds are widely used in human health and nutrition, at present they are mainly obtained by extraction from plants and extraction yields are low because most of these metabolites accumulate at low levels in plant cells....

Maintenance and support may account for as much as 60 to 75% of the total lifecycle cost of a manufacturing system. This paper presents a review on the predictive maintenance approaches, methods and tools in manufacturing systems and proposes an integrated predictive maintenance platform. This platform consists of three pillars, namely data acquisition and analysis, knowledge management, and a ...