نتایج جستجو برای: propafenone

تعداد نتایج: 393  

Journal: :Annals of internal medicine 2003
Robert L McNamara Leonardo J Tamariz Jodi B Segal Eric B Bass

PURPOSE This review summarizes the available evidence regarding the efficacy of medications used for ventricular rate control, stroke prevention, acute conversion, and maintenance of sinus rhythm, as well as the efficacy of electrical cardioversion and the use of echocardiography in patients with atrial fibrillation. DATA SOURCES The Cochrane Collaboration's database of controlled clinical tr...

Journal: :Chest 1990
E N Shen

(Chest 1990; 98:434-41) P ropafenone is a new class IC antiarrhythmic agent that has just l)een released in the United States for use in treatment o)f malignant ventricular arrhythmias (Rythmol, Knoll Pharmaceuticals, Whippany, New Jersey). It was first marketed in Europe in 1977, and has gained wide acceptance there and in Canada for the treatment of various types of ventricular and supraventr...

Journal: :American Journal of Gastroenterology 2019

Journal: :Biomedical Research and Therapy 2023

Junctional ectopic tachycardia (JET) occurs postoperatively or after catheter ablation in the region of Koch's triangle. The post-ablation incidence JET reported medical literature is very low. We report case a 13-year-old female patient who underwent slow pathway for atrioventricular node reentrant and subsequently developed JET. An accelerated automatic focus was found junction area due to ra...

Journal: :Journal of medicinal chemistry 2012
David Lowes Anupam Pradhan Lalitha V Iyer Toufan Parman Jason Gow Fangyi Zhu Anna Furimsky Andrew Lemoff W Armand Guiguemde Martina Sigal Julie A Clark Emily Wilson Liang Tang Michele C Connelly Joseph L Derisi Dennis E Kyle Jon Mirsalis R Kiplin Guy

Previously reported studies identified analogues of propafenone that had potent antimalarial activity, reduced cardiac ion channel activity, and properties that suggested the potential for clinical development for malaria. Careful examination of the bioavailability, pharmacokinetics, toxicology, and efficacy of this series of compounds using rodent models revealed orally bioavailable compounds ...

Journal: :European heart journal 2002
G B Lumer D Roy M Talajic A Couturier J Lambert N Frasure-Smith B Thibault M Dubuc P Gagné S Nattel

BACKGROUND Atrial fibrillation is the most common sustained cardiac arrhythmia, and engenders significant health care costs. The impact of various treatment options for atrial fibrillation on hospital costs has not been evaluated in a randomized trial. METHODS We analysed 1-year follow-up data on 392 patients randomized to low dose amiodarone (200 mg. day(-1)) or alternative first-line therap...

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