نتایج جستجو برای: proper305 traits the snp

تعداد نتایج: 16077062  

2015
Marcos S Lopes John W M Bastiaansen Luc Janss Egbert F Knol Henk Bovenhuis

Traditionally, exploration of genetic variance in humans, plants, and livestock species has been limited mostly to the use of additive effects estimated using pedigree data. However, with the development of dense panels of single-nucleotide polymorphisms (SNPs), the exploration of genetic variation of complex traits is moving from quantifying the resemblance between family members to the dissec...

Domestication and selection are processes that conserve the pattern of genetic diversities between and within populations. Identification of genomic regions that are targets of selection for phenotypic traits is one of the main aims of research in animal genetics. An approach for identifying divergently selected regions of the genome is to compare FST values among loci to estimate the genetic v...

Journal: :Genetical research 2002
Greg Gibson Trudy F C Mackay

Dissection of quantitative traits to the nucleotide level requires phenotypic and genotypic analysis of traits on a genome scale. Here we discuss the set of community-wide genetic and molecular resources, including panels of specific types of inbred lines and high density resequencing and SNP detection, that will facilitate such studies.

2013
Jihye Kim Ji-sun Kwon Sangsoo Kim

Gene set analysis is a powerful tool for interpreting a genome-wide association study result and is gaining popularity these days. Comparison of the gene sets obtained for a variety of traits measured from a single genetic epidemiology dataset may give insights into the biological mechanisms underlying these traits. Based on the previously published single nucleotide polymorphism (SNP) genotype...

2011
Sven Stringer Naomi R. Wray René S. Kahn Eske M. Derks

Complex diseases are often highly heritable. However, for many complex traits only a small proportion of the heritability can be explained by observed genetic variants in traditional genome-wide association (GWA) studies. Moreover, for some of those traits few significant SNPs have been identified. Single SNP association methods test for association at a single SNP, ignoring the effect of other...

2016
Habib U. Jan Amine Abbadi Sophie Lücke Richard A. Nichols Rod J. Snowdon Dragan Perovic

Genomic selection (GS) is a modern breeding approach where genome-wide single-nucleotide polymorphism (SNP) marker profiles are simultaneously used to estimate performance of untested genotypes. In this study, the potential of genomic selection methods to predict testcross performance for hybrid canola breeding was applied for various agronomic traits based on genome-wide marker profiles. A tot...

2015
Valdecy Aparecida Rocha da Cruz Flávio Schramm Schenkel Rodrigo Pelicioni Savegnago Natalia Vinhal Grupioni Nedenia Bonvino Stafuzza Mehdi Sargolzaei Adriana Mércia Guaratini Ibelli Jane de Oliveira Peixoto Mônica Corrêa Ledur Danísio Prado Munari Roberta Davoli

Apolipoprotein B (APOB) and Adiponectin Receptor 1 (ADIPOR1) are related to the regulation of feed intake, fat metabolism and protein deposition and are candidate genes for genomic studies in birds. In this study, associations of two single nucleotide polymorphisms (SNPs) g.102A>T (APOB) and g.729C>T (ADIPOR1) with carcass, bone integrity and performance traits in broilers were investigated. Ge...

2017
Pantaporn Supakankul Tanavadee Kumchoo Supamit Mekchay

OBJECTIVE This study was conducted to identify and evaluate the effective single nucleotide polymorphism (SNP) markers for fat deposition in the longissimus dorsi muscles of pigs using the amplified fragment length polymorphism (AFLP) approach. METHODS Sixty-four selective primer combinations were used to identify the AFLP markers in the 20 highest- and 20 lowest-intramuscular fat (IMF) conte...

2011
Tamuno Alfred Yoav Ben-Shlomo Rachel Cooper Rebecca Hardy Cyrus Cooper Ian J Deary Jane Elliott David Gunnell Sarah E Harris Mika Kivimaki Meena Kumari Richard M Martin Chris Power Avan Aihie Sayer John M Starr Diana Kuh Ian N M Day

Several age-related traits are associated with shorter telomeres, the structures that cap the end of linear chromosomes. A common polymorphism near the telomere maintenance gene TERT has been associated with several cancers, but relationships with other aging traits such as physical capability have not been reported. As part of the Healthy Ageing across the Life Course (HALCyon) collaborative r...

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