نتایج جستجو برای: prostate carcinomaو prostate specific antigen
تعداد نتایج: 1258516 فیلتر نتایج به سال:
Prostate Cancer Detection and Prognosis: From Prostate Specific Antigen (PSA) to Exosomal Biomarkers
Prostate specific antigen (PSA) remains the most used biomarker in the management of early prostate cancer (PCa), in spite of the problems related to false positive results and overdiagnosis. New biomarkers have been proposed in recent years with the aim of increasing specificity and distinguishing aggressive from non-aggressive PCa. The emerging role of the prostate health index and the 4Kscor...
Gold nanowires functionalized for electrochemical immunosensing were prepared and demonstrated to detect prostate specific antigen (PSA) with the sensitivity required in molecular and clinical diagnostics.
OBJECTIVE To evaluate if prostate specific antigen test attains validity standards required for screening in view of recent prostate cancer screening trial results. DESIGN Case-control study nested in longitudinal cohort. SETTING Västerbotten Intervention Project cohort, Umeå, Sweden. PARTICIPANTS 540 cases and 1034 controls matched for age and date of blood draw. MAIN OUTCOME MEASURE V...
Background and Aims: Prostate cancer is the second most common cancer in men worldwide in men. Matrix metalloproteinase 2 (MMP2) has a role in the invasion and destruction of the basement membrane and the extra-cellular matrix and facilitating the process of tumor cell invasion. The present study was conducted to compare the expression of MMP2 gene in prostate cancer (PCa) and benign prostatic ...
Background: Due to its biological properties, Prostate-specific membrane antigen (PSMA) is a good target for prostate cancer molecular imaging. The aim of this work was evaluate the role 18F PSMA Tomography–Computed Tomography (PET CT) in diagnosis and staging association with specific serum level. Methods: This prospective cohort performed on 30 individuals pathologically proven patients, seve...
PURPOSE To our knowledge the reasons for the high rates of prostate cancer in black American men are unknown. Genetic and lifestyle factors have been implicated. Better understanding of prostate cancer rates in West African men would help clarify why black American men have such high rates since the groups share genetic ancestry and yet have different lifestyles and screening practices. To esti...
BACKGROUND Long-term frozen storage may alter the results of prostate-specific antigen (PSA) measurements, mainly because of degradation of free PSA (fPSA) in vitro. We compared the effects of long-term storage on fPSA, total PSA (tPSA), and complexed PSA (cPSA) in serum vs EDTA-plasma samples. METHODS We measured fPSA and tPSA concentrations in matched pairs of archival serum and EDTA-plasma...
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