conclusions this is the first report of expression of cmv cp gene in iran, which is important for the preparation of anti-cmv antibody and paving the way for the use of the virus coat protein as a nanomaterial. results the identity of the expressed protein was confirmed by immunoassays such as western blot, dot-immunobinding assay (diba) and enzyme-linked immunosorbent assay (elisa) by the use ...

calprotectin, a calcium-bound protein complex, is abundant in the cytosol of neutrophils. it has been reported that this protein has an apoptotic activity in tumor cells. since calprotectin increases in colorectal cancer, this study was conducted to investigate, for the first time, the cytotoxicity/apoptotic effect of calprotectin on ht29/219 and sw742 colon carcinoma and adenocarcinoma cell li...

Dominant missense mutations in AQP5, encoding the water channel protein Aquaporin 5, underlie diffuse non-epidermolytic palmoplantar keratoderma (NEPPK), a rare skin condition characterized by thickening of epidermis palms and soles. Prior to this, AQP5 was only known be expressed sweat gland cells role this remains unclear. To study skin, we have two patient-derived keratinocyte cell lines exp...

recognition of the molecular mechanisms of camp action against dna damage-induced apoptosis can be useful to improve the efficacy of dna damaging therapeutic agents. considering the critical role of bcl-2-associated death promoter (bad) and p53 proteins in dna damage -induced apoptosis, the aim of this study was to assess the effect of camp-elevating agents on these proteins in doxorubicin-trea...

in this study the plasma levels of lipid peroxidation (lp) products, protein carbonyls and antioxidant capacity of plasma as judged by ferric reducing ability of plasma (frap assay) were compared in adult and weanling rats treated with vitamin k1 phylloquinone).

ABSTRACT: Actinomycetes are one of the important secondary metabolite producers. Researchers focused on exclusive marine areas for isolation and identification actinomycetes. The present study Nocardiopsis dassonovillei (ON627850) from TS Pettai region. potential strainTSP1 showed effective antibacterial activity against Haemophilus influenza. TSP1 isolates IC50 value 75.22 μg/ml antioxidant de...

objective(s): this study aimed to find out whether the chick cardiomyocyte micromass (mm) system could be employed to predict the teratogenecity of common environmental factors. different multivitamins and over the counter drugs were used in this study.   materials and methods: white leghorn 5-day-old embryo hearts were dissected and trypsinized to produce a cardiomyocyte cell suspension in dul...