Superparamagnetic iron oxide nanoparticles are candidate contrast agents for magnetic resonance imaging and targeted drug delivery. Biodistribution and toxicity assessment are critical for the development of nanoparticle-based drugs, because of nanoparticle-enhanced biological reactivity. Here, we investigated the uptake, in vivo biodistribution, and in vitro and in vivo potential toxicity of m...

Ultrafine hollow nanoparticles-based (7 nm) carbon nanoclusters (HNPCNCs) are developed by a facile and novel method. Benefiting from the ultrafine nanostructure, we have achieved close-packed storage of K metallic clusters with diameter 7 nm has been observed for first time through ex TEM. In K-ion batteries, HNPCNCs anodes deliver an ultrahigh capacity 269.8 mA h g?1 at 0.5 A after 200 cycles...

The Electrochemical Society Interface • Fall 2002 olecular magnetism is an evolving discipline relying on quantum chemistry, orbitals and Hamiltonians, organic and coordination chemistries, physics, and devices. Among the exciting molecule-based magnetic systems, Prussian blue analogues occupy a peculiar position. Prussian blue itself was described for the first time in 1704. Since this time, t...

Purpose: The presence of tumor-associatedmacrophages (TAM) in breast cancer correlates strongly with poor outcome. The purpose of this study was to develop a clinically applicable, noninvasive diagnostic assay for selective targeting and visualization of TAMs in breast cancer, based on magnetic resonanceI and clinically applicable iron oxide nanoparticles. Experimental Design: F4/80-negativemam...

We designed and synthesized novel theranostic nanoparticles that showed the considerable potential for clinical use in targeted therapy, and non-invasive real-time monitoring of tumors by MRI. Our nanoparticles were ultra-small with superparamagnetic iron oxide cores, conjugated to erlotinib (FeDC-E NPs). Such smart targeted nanoparticles have the preference to release the drug intracellularly ...

We report the mechanisms for reversible and repeatable spin transition in a Prussian blue analog crystal, KCo[Fe(CN)6], derived from first-principles calculations. The forward and reverse transitions are initiated by metal-to-metal charge transfer, followed by the d-electron rearrangement at the Co center. Further, these transitions are strongly correlated with bond lengths within the crystal l...