Morphologic analyses of lungs from infants who died of severe aortic stenosis shortly after birth have shown increased pulmonary vascular smooth muscle and an increased number of pulmonary resistance vessels. These findings have been thought to be caused by in utero pulmonary venous, pulmonary arterial or right ventricular hypertension. To study this problem in the fetus, we created aortic sten...

BACKGROUND Pulmonary stenosis is common in children with complex congenital heart diseases. Proper management of this problem, especially postoperatively, is still controversial. This study was designed to assess the rate and determinants of success or failure of balloon angioplasty for such lesions. METHODS Clinical and hemodynamic data from 40 pediatric patients (24 boys and 16 girls) with ...

Morphologic analyses of lungs from infants who died of severe aortic stenosis shortly after birth have shown increased pulmonary vascular smooth muscle and an increased number of pulmonary resistance vessels. These findings have been thought to be caused by in utero pulmonary venous, pulmonary arterial or right ventricular hypertension. To study this problem in the fetus, we created aortic sten...

The records of 15 infants with pulmonary atresia and 19 infants with critical pulmonic stenosis and intact ventricular septum, all under 1 year of age, have been reviewed. Symptoms started earlier and were more severe in the group with pulmonary atresia. All patients showed arterial unsaturation, and many had congestive heart failure. The electrocardiogram was the most helpful tool in different...

Peripheral pulmonary artery stenosis is a rare form of congenital heart disease frequently associated with Williams and Alagille syndromes. Patients with this disease typically have systemic level right ventricular pressures secondary to obstruction at the lobar, segmental, and subsegmental branches. The current management of patients with peripheral pulmonary artery stenosis remains somewhat c...

It has been observed that in certain cases of mitral stenosis the increase in pulmonary arterial pressure is out of proportion to the pressures on the venous side of the pulmonary circulation. This increase is due to narrowing of the pulmonary arterioles (Dexter et al., 1950; Baker et al., 1952; Ferrer et al., 1952), which may result either from organic changes in the pulmonary arterioles (inti...

pure or predominant mitral stenosis before and 34 to 40 months after valvotomy. The patients were divided into 3 groups: pure mitral stenosis without increased pulmonary vascular resistance (group I, n =33), pure mitral stenosis with abnormal increase of pulmonary vascular resistance (group II, n= I2), and predominant mitral stenosis with mild insufficiency (group III, n= 9; all patients underg...

The records of 15 infants with pulmonary atresia and 19 infants with critical pulmonic stenosis and intact ventricular septum, all under 1 year of age, have been reviewed. Symptoms started earlier and were more severe in the group with pulmonary atresia. All patients showed arterial unsaturation, and many had congestive heart failure. The electrocardiogram was the most helpful tool in different...