Tinnitus is a common disorder, it can be classified as pulsatile and non-pulsatile or objective and subjective. Pulsatile tinnitus is less common than non-pulsatile and can be due to vascular tumour such as glomus or vascular abnormality. We presented an interesting case of a 30 year-old Malay lady with a two-year history of pulsatile tinnitus which was worsening in three months duration. It wa...

BACKGROUND Pulsatile GnRH therapy is the gold standard treatment for ovulation induction in women having functional hypothalamic amenorrhea (FHA). The use of pulsatile GnRH therapy in FHA patients with polycystic ovarian morphology (PCOM), called "FHA-PCOM", has been little studied in the literature and results remain contradictory. The aim of this study was to compare the outcomes of pulsatile...

OBJECTIVE Leptin is known to play an important role in pubertal development in humans, probably acting as one permissive factor for the onset of puberty. Leptin serum concentrations change during pubertal development and an initial increase before the onset of puberty has been reported. The underlying mechanism for this increase in leptin levels is unknown. We hypothesized that the pulsatile re...

PURPOSE To evaluate the feasibility and accuracy of Roentgen stereophotogrammetric analysis (RSA) versus computed tomography (CT) for detecting stent-graft migration in an in vitro pulsatile circulation model and to study the feasibility of a nitinol endovascular clip (NEC) as an aortic wall reference marker for RSA. METHODS An aortic model with stent-graft was constructed and connected to an...

In this day and age of cardiovascular surgery with cardiopulmonary bypass (CPB), the perfusionist strives to maintain or mimic normal physiologic parameters such as blood gases, electrolytes, blood flows and so on. The surgical team employes such myocardial protection techniques as topical cooling and cardioplegia. The anaesthesiologist endeavours to maintain hemodynamic and respiratory paramet...

Objective: Patients with single functional ventricles have a bad prognostic; most result in heart failure even after operation. The right heart bypass operations, except for right atrium and right ventricle connections, lack pulsatile flow and the volume returning to the common ventricle is low. To solve this problem, we tried to experimentally create a pulmonary ventricle which produces pulsat...

Pig oocytes matured in vitro were parthenogenetically activated using nitric oxide donor SNAP (2mM). Continuous treatment successfully activated the oocytes only after more than 12 hours of exposure. Pulsatile treatments during which oocytes were repeatedly exposed to 2mM SNAP for a short time (10, 20 or 30 minutes) were more efficient with regard to the activation rate, even when the total exp...

OBJECTIVE Pulsatile tinnitus caused by dural venous sinus (DVS) stenosis is a newly identified form of tinnitus. Its persistent nature can severely affect patients' sleep and quality of life, leading to depression in severe cases. The aim of this report is to investigate the efficacy and safety of angioplasty and stenting in treating this form of tinnitus. STUDY DESIGN Retrospective review. ...

PURPOSE To validate conventional phase-contrast MRI (PC-MRI) measurements of steady and pulsatile flows through stenotic phantoms with various degrees of narrowing at Reynolds numbers mimicking flows in the human iliac artery using stereoscopic particle image velocimetry (SPIV) as gold standard. MATERIALS AND METHODS A series of detailed experiments are reported for validation of MR measureme...

This study compares the effects of pulsatile and nonpulsatile perfusion upon myocardial contractility. After 2 hr of ventricular fibrillation, control animals demonstrated a 37% decrease in left ventricular force, a 48% decrease in left ventricular compliance, and an increase in endomyocardial water content. On the other hand, after 2 hr of ventricular fibrillation, animals undergoing pulsatile...