A case of eosinophilic fasciitis is presented. The clinical, biochemical and pathological findings were similar to those described in the literature. The history of violent exercise present in most patients was absent in our case. Immunofluorescent studies of the fascial and muscular biopsy showed deposits of C3 and fibrinogen in the vessel walls. The information of E rosettes by T lymphocytes ...

STUDY OBJECTIVES To assess the validity of purified protein derivative (PPD) readings by patients and trained health-care professionals as compared with a calibrated model. DESIGN AND PARTICIPANTS Survey of a group of patients, nurses, medical assistants, and physicians at five neighborhood health centers in the Bronx, NY. INTERVENTIONS Participants were asked to read a calibrated model wit...

The method used to produce "Connaught" tuberculin purified protein derivative (PPD) is described. The tuberculin PPD for the multiple-puncture method was shown to be stable for at least 24 months at 5 C; tuberculin PPD for the intracutaneous method was shown to be stable at 5 C and 24 C for a period of 18 months in the presence of Tween 80. Evans blue or brillant vital red was added to tubercul...

Considering the positive results of homeopathic therapy of bovine mastitis, the presented study should evaluate the effects of two standardized homeopathic methods in sub-clinical mastitis using a prospective randomized double-blind placebo control study design. A number of 124 dairy cows from 17 herds with increased somatic cell count were selected and randomly associated to 5 treatment groups...

GUINEA PIGS SENSITIZED WITH TUBERCLE BACILLI DEMONSTRATE A DUAL ALLERGIC RESPONSE MEDIATED BY TWO CHEMICALLY DISTINCT PLASMA FRACTIONS: 1. Antibody to tuberculopolysaccharide is located exclusively in fraction II (gamma globulin). This fraction will passively transfer systemic anaphylaxis and urticarial type skin reactivity to tuberculopolysaccharide, and contains the Middlebrook-Dubos antibody...

ABSTRACT Herein, we describe the synthesis and characterization of a conjugated donor-acceptor copolymer consisting of a pyrrolopyridazinedione (PPD) acceptor unit, and a benzodithiophene (BDT) donor unit. The polymerization was done via a Stille cross-coupling polycondensation. The resulting PPD-BDT copolymer revealed an optical bandgap of 1.8 eV and good processability from chlorobenzene solu...

OBJECTIVE To illustrate the utility of statistical monitoring boundaries in meta-analysis, and provide a framework in which meta-analysis can be interpreted according to the adequacy of sample size. To propose a simple method for determining how many patients need to be randomized in a future trial before a meta-analysis can be deemed conclusive. STUDY DESIGN AND SETTING Prospective meta-anal...

OBJECTIVE Understanding human immunity to Mycobacterium tuberculosis (Mtb) during different stages of infection is important for development of an effective tuberculosis (TB) vaccine. We aimed to evaluate immunity to Mtb infection by measuring immune responses to selected Mtb antigens expressed during different stages of infection over time and to observe sustainability of immunity. METHODS I...

BACKGROUND Treatment of latent infection is needed to protect HIV-infected individuals against tuberculosis. A previous report addressed short-term efficacy of three regimens in HIV-infected adults. We now report on long-term efficacy of the study regimens. METHODS Three daily self-administered regimens were compared in a randomized placebo-controlled trial in 2736 purified protein derivative...

A 6-year-old boy developed a skin eruption 10 days after application of a temporary tattoo advertised as a "natural black henna tattoo." The eruption was a delayed hypersensitivity reaction to the tattoo ink. The textile dye paraphenylenediamine (PPD) is a common industrial allergen and can be found in some temporary tattoo inks. This case describes the reaction and reviews the international li...