HS: hidradenitis suppurativa IL: interleukin PAPA: pyoderma gangrenosum with pyogenic sterile arthritis and cystic acne PAPASH: pyoderma gangrenosum with pyogenic sterile arthritis, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum with cystic acne and hidradenitis suppurativa PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is a neutrophilic dermatitis, the prevalenc...

Pyoderma gangrenosum and Sweet's syndrome are classified as neutrophilic dermatoses as they exhibit intense dermal inflammatory infiltrates composed of neutrophils with little evidence of a primary vasculitis. They share several characteristics and respond to immunosuppressives. Aetiology is felt to represent a manifestation of altered immunologic reactivity. Patients with both conditions concu...

A case is presented of pyoderma gangrenosum, describing its characteristic features with particular reference to the phenomenon of pathergy, which considerably limits the surgical approach to the disease. After an account of the numerous skin ulcerations that have to be taken into consideration in order to make a differential diagnosis, it is noted that pyoderma gangrenosum can only on rare occ...

OBJECTIVE To determine the health impact of swimming pools built with the aim of improving quality of life and reducing high rates of pyoderma and otitis media. DESIGN Intervention study assessing prevalence of ear disease and skin infections before and at six monthly intervals after opening of swimming pools. SETTING Two remote Aboriginal communities in Western Australia. PARTICIPANTS 84...

BACKGROUND Concern has been raised regarding the potential contributions of veterinary antimicrobial use to increasing levels of resistance in bacteria critically important to human health. Canine pyoderma is a frequent, often recurrent diagnosis in pet dogs, usually attributable to secondary bacterial infection of the skin. Lesions can range in severity based on the location, total area and de...

PG: pyoderma gangrenosum TNF: tumor necrosis factor Pyoderma gangrenosum (PG) is a rare, neutrophilic, ulcerative dermatosis without a therapeutic gold standard. Vegetative PG is a chronic superficial variant, which is more indolent and typically responds well to treatment. Here we describe a patient with a 3-year history of uncharacteristically recalcitrant vegetative PG who responded to aprem...

We describe a 62-year old man diagnosed with pyoderma gangrenosum following a traumatic injury to the hand. The patient was originally misdiagnosed with cellulitis and his condition did not improve with oral or intravenous antibiotics. The wound dramatically improved following institution of intravenous steroids. Pyoderma gangrenosum should be considered in the differential of a non-healing cel...

Severe. lifelong, unresolv;ng pyoderma gangrenosum occurs in association with recurrent episodes of sterile pyoarthrosis and the presence of a serum factor (called "streaking leukocyte factor") (1) responsible for enhancing random migration of purified human neutrophils and mononuclear leukocytes in vitro. Pyoderma gangrcnosum is only one feature of this unusual disease. Minor trauma of any sor...