Central neuropathic pain (CNP) is considered as a complicated sensory disturbance which many multiple sclerosis (MS) patients suffer from. Although monophasic experimental autoimmune encephalomyelitis (EAE) mouse model is a gold standard model in preclinical research of MS, severe movement deficit could confound pain behaviors evaluation over the disease course. In this study, complete Freund&r...

We consider some fundamental properties of QS-algebras and show that (1) the theory of QS-algebras is logically equivalent to the theory of Abelian groups, that is, each theorem of QS-algebras is provable in the theory of Abelian groups, and conversely, each theorem of Abelian groups is provable in the theory of QS-algebras; and (2) a G-part G(X) of a QSalgebra X is a normal subgroup generated ...

Background Cardiovascular magnetic resonance (CMR) flow quantification for determining the ratio of flow between the pulmonary and systemic circulation (Qp/Qs) is used to quantify cardiac shunts. However, both the accuracy and precision of Qp/Qs can be influenced by measurement errors in flow quantification. Post-processing methods for stationary tissue background correction have been proposed ...

In this paper we first introduce the Fock-Guichardet formalism for the quantum stochastic (QS) integration, then the four fundamental processes of the dynamics are introduced in the canonical basis as the operator-valued measures, on a space-time σ-field FX, of the QS integration. Then rigorous analysis of the QS integrals is carried out, and continuity of the QS derivative D is proved. Finally...

Results TCPC patients had significantly lower systemic blood flow(Qs) at rest (2.7±0.6 vs. 3.6±0.7 L/min/m2, p<0.001) and during exercise (3.4±1.0 vs. 4.9±0.9 L/min/m2, p<.0001), than healthy controls. The increase in Qs with exercise was also significantly lower in patients, than in healthy controls (0.6 vs. 1.2 L/min/m2, p<0.02). Absolute collateral flow did not change in TCPC patients during...

conclusions we found that ei and qp/qs ratio are significantly and positively associated and qp/qs ratio can be easily estimated by measuring ei in secundum type asd patients. background one of the inclusion criteria for applying atrial septal defect (asd) closing procedure is an increased pulmonary-to-systemic blood flow ratio (qp/qs). eccentricity index (ei) is associated with ventricular dys...

When producing recombinant proteins, the use of Escherichia coli strain BL21(DE3) in combination with the T7-based pET-expression system is often the method of choice. In a recent study we introduced a mechanistic model describing the correlation of the specific glucose uptake rate (qs,glu) and the corresponding maximum specific lactose uptake rate (qs,lac,max) for a pET-based E. coli BL21(DE3)...

Many Gram-negative pathogens have the ability to produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Strategies to inhibit QS are promising for the control of infectious diseases or antibiotic resistant bacterial pathogens. The aim of the present study was to e...

Like any form of cooperative behavior, quorum sensing (QS) in bacteria is potentially vulnerable to cheating, the occurrence of individuals that contribute less but still profit from the benefits provided by others. In this paper, we explore the evolutionary stability of QS as a regulatory mechanism of antibiotics production in a spatially structured population, using cellular automaton (CA) mo...

Many different Gram negative bacteria employ N-acylhomoserine lactones (AHLs) as diffusible signal molecules which enable bacterial populations to co-ordinate gene expression as a function of cell population density. Such co-ordinated community behavior, termed “quorum sensing” (QS) regulates diverse physiological processes including secondary metabolite production, motility, DNA transfer and p...