نتایج جستجو برای: quaternary mixture of drugs
تعداد نتایج: 21181430 فیلتر نتایج به سال:
Stereochemistry can be said to have begun in 1848 when Pasteur observed that crystals of sodium ammonium tartrate obtained by slow recrystallisation at room temperature were of two mirror image crystallographic forms. He was able to pick out these two forms by hand and show that solutions of equal concentration caused an equal and opposite rotation of plane polarised light. The rotation disappe...
introduction: although patients do not experience sever pain after laparoscopic surgery, most of them experience acute or chronic pain afterward. while conventional pain killers including nsaid and narcotics in laparoscopic surgery have specific side effects, their application is inevitable. this study compares the efficacy of local anesthetic drugs and conventional pain killers in post-operati...
Numerous psychotropic drugs exist as a mixture of 2 mirror-image stereoisomers of each other, each called an enantiomer and the mixture called a racemate. Often the drug can be improved when only 1 of the enantiomers is administered.
The present study evaluated the single and mixed toxicities of commonly used antifouling biocides (copper pyrithione, Sea nine 211, dichlofluanid, tolylfluanid, and Irgarol 1051) on the early embryogenesis of sea urchin Strongylocentrotus intermedius. Their toxicities were quantified in terms of the median effective concentration (EC50) reducing the embryogenesis success by 50%. For individual ...
Simple, selective and sensitive high-performance thin layer chromatographic (HPTLC) method has been developed and validated for the simultaneous determination of hydrochlorothiazide (HCZ) in the presence of its impurities (chlorothiazide (CT) and salamide (DSA)), in two quaternary mixtures with benazepril hydrochloride (BZ) or amiloride hydrochloride (AM). The separation was carried out on HPTL...
Introduction: Quaternary basalts are one of the last signs of magmatism in Iran, some of which are related to deep fractures and active faults in the Quaternary. Quaternary basalts of Tabas are very important due to their high expansion and location in eastern Iran, and are located 140 km south east of Tabas city and according to the proposed divisions are part of the Lut zone. The aim of this...
many properties of chemicals depend on their stereochemistry. among these, the effects of stereoisomerism on percutaneous absorption of drugs are not well studied. we have previously shown that permeation of tretinoin and isotretinoin (two geometric isomers) through hydrophilic enhancers-treated rat skin is stereoselective. as, depending on their lipophilicity, penetration enhancers can change ...
Conjugation of many primary, secondary, and tertiary amine-containing xenobiotics with glucuronic acid can result in the formation of N-glucuronide metabolites. For carcinogenic arylamines and their N-hydroxylated metabolites, N-glucuronidation can result in the formation of either inactive metabolites or labile conjugates, which can be transported to their target tissue (urinary bladder) where...
Alkylation reactions of α-carboxylate phosphabetaines were carried out and studied to enhance the biological activity previously synthesized carboxylate phosphabetaines. As a result these reactions, original structure was destroyed with formation quaternary salts phosphonium triiodide. The composition confirmed by complex physical research methods, including NMR, IR spectroscopy, elemental anal...
The possibility of removing certain pharmaceuticals from wastewater was tested using Octolig, a commercially available material with polyethyldiamine moieties covalently attached to high-surface area silica gel. Selected drugs and drug models were subjected to column chromatography for removal by means of ion encapsulation, the effectiveness of which would depend upon having appropriate anioni...
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