L-glycine and L-cysteine, exhibit strong inhibition of partial purified PPO of wild pear. The concentration of L-glycine inhibiting PPO activity by 50% (IC ) was 0.8 and 0.5 mM for catechol oxidation and 50 0.75 and 0.5 mM for pyrogallol oxidation at pH 5 and 7, respectively. IC for L-cysteine calculated, 0.6 and 0.35 50 for catechol oxidation and 0.55 and 0.75 mM for pyrogallol oxidation at pH...

Effects of ATP-sensitive potassium (КATP) channel opener diazoxide (1 mg/kg) and inhibitor 5-hydroxydecanoate (5 mg/kg) on ADP-induced mitochondrial respiration by Chance under adrenaline myocardium dystrophy were studied. The process of lipid peroxidation in the liver also was investigated. Substrates of oxidation, such as 0.35 mМ succinate and 1 mМ α-ketoglutarate, were used. To define the ro...

It has been shown in our previous study that monoamine oxidase (MAO) activity in different brain regions are correlated with a microsomal oxidation phenotype. The data obtained in this study, using the microsomal oxidation inhibitor SKF525, and using animals with different duration of hexobarbital sleep, has shown that increased intensity of microsomal oxidation might be associated with increas...

The cytochrome bc1 complex resides in the inner membrane of mitochondria and transfers electrons from ubiquinol to cytochrome c. This electron transfer is coupled to the translocation of protons across the membrane by the protonmotive Q cycle mechanism. This mechanism topographically separates reduction of quinone and reoxidation of quinol at sites on opposite sites of the membrane, referred to...

The antimycin-sensitive ubisemiquinone radical (QC) of the ubiquinol-cytochrome c oxidoreductase of submitochondrial particles and chromatophores of Rhodopseudomonas sphaeroides Ga has been studied by a combination of redox potentiometry and EPR spectroscopy. This g = 2.005 radical signal appears at physiological pH values and increases in intensity with increasing pH up to pH 7.6 in submitocho...

Up to six differently substituted highly challenging angularly-oxygenated tricyclic core models of natural angucyclinones were stereoselectively synthesized from a common p-quinol intermediate obtained from Oxone-mediated oxidative dearomatization of the corresponding tricyclic phenol.

'Candidatus Methylomirabilis oxyfera' is a denitrifying methanotroph that performs nitrite-dependent anaerobic methane oxidation through a newly discovered intra-aerobic pathway. In this study, we investigated the response of a M. oxyfera enrichment culture to oxygen. Addition of either 2% or 8% oxygen resulted in an instant decrease of methane and nitrite conversion rates. Oxygen exposure also...