نتایج جستجو برای: rabeprazole sodium
تعداد نتایج: 187990 فیلتر نتایج به سال:
Logical strategy is the heart of drug investigation. The current work endeavored to foster precise, straightforward, and delicate techniques for concurrent assessment rabeprazole levosulpiride. overlay range levosulpiride display λmax 288 nm 282 LEVO RABE. Standard adjustment bends were straight with connection coefficient (r) values in scope 0.9998-0.9997 at all chosen frequencies. prec...
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic cytochrome P450 (P450) system. To compare the potency and specificity of the currently used PPIs (i.e., omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole) as inhibitors of four cytochrome P450 enzymes (CYP2C9, 2C19, 2D6, and 3A4), we performed in ...
OBJECTIVE We investigated factors related to proton pump inhibitor (PPI) -refractory gastroesophageal reflux disease (GERD) symptoms, particularly with respect to acid, the CYP2C19 genotype and psychological aspects. METHODS Patients with an Frequency Scale for the Symptoms of GERD (FSSG) score of ≥8 after the initial treatment were switched to therapy with rabeprazole at a dose of 20 mg once...
Bilayer tablets of Domperidone (IR) Rabeprazole (SR) were formulated for the management of gastro esophageal disorder.Immediate layer of Domperidone formulated using Tulsion T-339 as super disintegrant. For sustained release of Rabeprazole HPMC as the rate controlling polymers was used. Preformulation studies were performed prior to compression. The individual layers of the bilayer tablets were...
Background: Helicobacter pylori infection is a worldwide problem with more than half of the world's population in both developed and developing countries are infected this organism. The best-characterized H. adhesins, Blood group antigen binding Adhesin (BabA) Sialic acid (SabA) virulent factors which facilitate adhesion bacteria to host cells. Methods: We determined affinities selected existin...
Clopidogrel is a mainstay therapy in the cardiovascular (CVS) pharmacology for the prevention of the stent thrombosis and myocardial infarctions following many different types of coronary syndromes.The conversion of clopidogrel; which is a prodrug, to its active metabolite is mediated by the cytochrome P450 (CYP).The CYP450 metabolic activation of clopidogrel has proposed about if the competiti...
BACKGROUND Helicobacter pylori (H. pylori) treatment remains a challenge for physicians. Although highly effective, the standard sequential therapy fails in a certain number of patients. Moreover, the cure rate following a levofloxacin-amoxicillin second-line triple therapy seems to be decreasing. We tested the efficacy of modified 10-day sequential therapy, and an intensified levofloxacin-amox...
BACKGROUND Eradication rates of Helicobacter pylori with standard triple therapy are disappointing, and studies from several countries confirm this poor performance. AIM To assess the eradication rate of a new sequential treatment regimen compared with conventional triple therapy for the eradication of H. pylori infection. METHODS One thousand and forty-nine dyspeptic patients were studied ...
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