Background: TNF-α is a multifunctional proinflammatory cytokine and TGF-β1 is a secretory protein controlling epithelial proliferation and differentiation. Keratocyst presents an aggressive behavior and a growth mechanism different from that of radicular cyst. Aim: In this line, the present study aimed at evaluating TNF-α and TGF-β1 level and its association with histopath...

Introduction: Odontogenic cysts are characterized by an expansile non–infiltrative growth through several mechanisms which include presence of mast cells in the capsule. The mast cells can be demonstrated histochemically as well as immunohistochemically. Aim and Objectives: The primary objective of the study was to analyze the presence and distribution of mast cells in radicular cyst, dentigero...

Lumbar synovial cysts are an uncommon cause of back pain and radiculopathy, usually manifesting with gradual onset of symptoms, secondary to involvement of the spinal canal. Rarely, intracyst hemorrhage occurs, and may acutely present as radicular - or even spinal cord - compression syndrome. Synovial cysts are generally associated with degenerative facets, although the pathogenesis has not bee...

Perineural or Tarlov cysts were first described by Tarlov [1] in 1938 during his autopsy studies of the filum terminale [1]. Studies have shown the prevalence of these cysts to vary from 4.6% in some to upto 9% in others [2,3]. Although most of these lesions are asymptomatic, on rare occasions, they may cause local or radicular pain, dysesthesia or paresthesia, paresis and bladder or bowel dysf...

abstract introduction. p53 has been known as a tumor suppressor gene and also ki-67 is a cell cycle regulator. the aim of present study was to investigate p53 and ki-67 protein expression in the epithelial lining of odontogenic cysts and its correlation with their biologic behavior and the degree of inflammation within the cyst wall. methods. p53 and ki-67 immunoreactivity in 58 odontogenic cys...

OBJECTIVE The objective of this study was to experimentally induce inflammatory cysts in an animal model so as to test the hypothesis that radicular cysts develop via the "abscess pathway." METHODOLOGY Twenty-eight perforated custom-made Teflon cages were surgically implanted into defined locations in the back of 7 Sprague Dawley rats. A week after the implantation of the cages, a known quant...

Aim: The aim of this study is to review the literature concerning malignant transformation of radicular cyst. Material and Method: A literature search using MEDLINE, accessed via the National Library of Medicine PubMed interface (http://www.ncbi.nlm.nih.gov/pubmed), searching for articles relating to the malignant transformation of radicular/residual cyst written in English from 1960-2013. Resu...

objectives: the purpose of this study was to determine the frequency of all odontogenic cysts (ocs) along with age range, gender distribution, and the site of involvement over a 10-year period (march 2001 to march 2011) and to compare these data with findings from other surveys. methods: the archives of departments of oral and maxillofacial pathology from shahid beheshti and tehran university o...

background & objectives: odontogenic cysts are among the most frequent destructive lesions of jaws which their pathogenesis and growth mechanism are not cleared. with respect to different roles of mast cells, they may play a role in the pathogenesis and growth of odontogenic cysts. the aim of present study was to evaluate mast cells in the most common odontogenic cyst. methods: thirty  para...