By using stereospecifically double-labelled radioactive mevalonates it was shown that betulaprenols-6 to -9, found in the woody tissue of Betula verrucosa, each contain three biogenetically trans-isoprene residues and that the remaining residues are biogenetically cis. The results obtained with these radioactive mevalonates also indicated that the activity of isopentenyl pyrophosphate isomerase...

BACKGROUND Radioactive stents have been reported to reduce in-stent neointimal thickening. An unexpected increase in neointimal response was observed, however, at the stent-to-artery transitions, the so-called "edge effect." To investigate the factors involved in this edge effect, we studied stents with 1 radioactive half and 1 regular nonradioactive half, thereby creating a midstent radioactiv...

This paper reports on a study of indoor air quality in homes and child care facilities in non-metropolitan counties of New York State. Specific pollutants examined were lead, radon, carbon monoxide, asbestos, and mold. Some homes had high levels of pollutants, and certain pollutants were significantly and negatively correlated with household income. High levels of pollutants also were observed ...

Although there are a number of reports concerning the uptake of various radioactive nuclides from surrounding water by aquatic organisms1), the quantitative informations on the transfer of radioactive substances through aquatic food chains have been scarcely obtained until now. In near future, in accordance with the rapid developement of the peaceful utilization of atomic energy in Japan, the p...

THE SUCCESSFl'L application of radioactive indicators in physiology caused the early introduction of a radioactive component into the erythrocytes and their use in blood volume determinations. While this method has found application in animal experiments, it is not very suitable for determination of the blood volume of humans, since ironlabeled red corpuscles can only be obtained in vivo, and t...

BACKGROUND Many investigations of the adverse health effects of multiple air pollutants analyze the time series involved by simultaneously entering the multiple pollutants into a Poisson log-linear model. This method can yield unstable parameter estimates when the pollutants involved suffer high intercorrelation; therefore, traditional approaches to dealing with multicollinearity, such as princ...

OBJECTIVE Though many contaminants are released into the atmosphere, in the US only six air pollutants-ozone, particulate matter, sulfur dioxide, carbon monoxide, nitrogen dioxide, and lead-are closely monitored and carefully assessed for health significance. Other pollutants, even if highly toxic, are neither widely monitored nor routinely assessed at the national level. The goal of this study...

Dilution is the mixing of radioactive waste with non-radioactive material, whereas downblending is the mixing of high-level radioactive waste with low-level radioactive waste. These processes have been applied predominantly at nuclear sites as part of the decontamination procedures for the disposal of blended wastes in licensed facilities. Proper health and safety assessments should be carried ...

BACKGROUND Environmental air pollutants are inhaled as complex mixtures, but the long dominant focus of monitoring and research on individual pollutants has provided modest insight into pollutant interactions that may be important to health. Trends toward managing multiple pollutants to maximize aggregate health gains place increasing value on knowing whether the effects of combinations of poll...

BACKGROUND Air pollution contributes significantly to global increases in mortality, particularly within urban environments. Limited knowledge exists on the mechanisms underlying health effects resulting from exposure to pollutant mixtures similar to those occurring in ambient air. In order to clarify the mechanisms underlying exposure effects, toxicogenomic analyses are used to evaluate genome...