نتایج جستجو برای: rala software

تعداد نتایج: 437527  

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2007

Journal: :Antimicrobial agents and chemotherapy 2011
Jia Liu Michael D Miller Robert M Danovich Nathan Vandergrift Fangping Cai Charles B Hicks Daria J Hazuda Feng Gao

Raltegravir is highly efficacious in the treatment of HIV-1 infection. The prevalence and impact on virologic outcome of low-frequency resistant mutations among HIV-1-infected patients not previously treated with raltegravir have not been fully established. Samples from HIV treatment-experienced patients entering a clinical trial of raltegravir treatment were analyzed using a parallel allele-sp...

Journal: :EMBO reports 2016
Kirsten Tracy Panagiotis D Velentzas Eric H Baehrecke

Autophagy traffics cellular components to the lysosome for degradation. Ral GTPase and the exocyst have been implicated in the regulation of stress-induced autophagy, but it is unclear whether they are global regulators of this process. Here, we investigate Ral function in different cellular contexts in Drosophila and find that it is required for autophagy during developmentally regulated cell ...

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