نتایج جستجو برای: rare bleeding disorder

تعداد نتایج: 857287  

2012
Nazli Hossain Tahir S. Shamsi Adeel Feroz

Glanzmann's thromboasthenia (GT) is a rare platelet disorder, due to membrane defects involving glycoprotein GP IIb/IIIa complex. Symptoms appear in infancy with episodes of bruising, gingival bleeding, epistaxis, or at the time of menarche acute episode of uterine bleeding. Hormonal therapy and antifibrinolytic agents are first-line treatment. Platelet transfusion is given to control hemorrhag...

2013
Guillermo Salinas-Escudero Rosa María Galindo-Suarez María Fernanda Carrillo-Vega Emilio Muciño-Ortega Federico Gómez

Hemophilia is a rare bleeding disorder that is attributed to a defi ciency of coagulation factors VIII, IX and XI. This defi ciency leads to a tendency of moderate to severe bleeding. This disorder occurs mainly in males, who represent 97.32% of cases.1 Hemophilia A is caused by a factor VIII (FVIII) defi ciency.2 Globally it is estimated that the prevalence of hemophilia A in 2012 was 363,668 ...

2016
Yoshikazu Nagase Shuji Ueda Hitomi Matsunaga Aya Yoshioka Yoshiyuki Okada Tomohisa Machida Keiichi Nakata Fuka Mima Risato Takeda Daisuke Hayashi Sadaharu Iio Kohei Okita Hiroyuki Narahara Yuichi Yasunaga Yoshiaki Inui Sumio Kawata

BACKGROUND Acute compartment syndrome is an orthopedic emergency requiring urgent fasciotomy to prevent irreversible damage. In hematological malignancies, acute compartment syndrome caused by severe soft tissue bleeding is extremely rare. We present a patient with chronic-phase chronic myeloid leukemia who had acute compartment syndrome caused by severe soft tissue bleeding in her right forear...

Journal: :Haematologica 2009
Angela Huth-Kühne Francesco Baudo Peter Collins Jørgen Ingerslev Craig M Kessler Hervé Lévesque Maria Eva Mingot Castellano Midori Shima Jean St-Louis

Acquired hemophilia A (AHA) is a rare bleeding disorder characterized by autoantibodies directed against circulating coagulation factor (F) VIII. Typically, patients with no prior history of a bleeding disorder present with spontaneous bleeding and an isolated prolonged aPTT. AHA may, however, present without any bleeding symptoms, therefore an isolated prolonged aPTT should always be investiga...

2014
Yashar Ilkhchoui Eugene Koshkin Jimmy J Windsor Timothy R Petersen Matthew Charles Jeffery D Pack

INTRODUCTION Acquired hemophilia A is a rare bleeding disorder with a high mortality rate. Diagnosis and treatment of this disorder can be very challenging to anesthesiologists because of lack of a personal or familial abnormal bleeding history. CASE PRESENTATION We report a 60-year-old woman who presented to the operating room for an urgent fasciotomy. She was initially diagnosed to have com...

Journal: :Haemophilia : the official journal of the World Federation of Hemophilia 2008
R Mehta A D Shapiro

Plasminogen activator inhibitor type 1 (PAI-1) is an important component of the coagulation system that down-regulates fibrinolysis in the circulation. Reduced PAI-1 levels may result in increased fibrinolysis and an associated bleeding diathesis. Clear documentation of PAI-1 deficiency as a cause of a bleeding disorder has been rare. PAI-1 was initially identified in the 1980s, and the first r...

2017
Tetsuro Uchida Azumi Hamasaki Eiichi Ohba Atsushi Yamashita Jun Hayashi Mitsuaki Sadahiro

BACKGROUND Heyde syndrome is known as a triad of calcific aortic stenosis, anemia due to gastrointestinal bleeding from angiodysplasia, and acquired type 2A von Willebrand disease. This acquired hemorrhagic disorder is characterized by the loss of the large von Willebrand factor multimers due to the shear stress across the diseased aortic valve. The most frequently observed type of bleeding in ...

Journal: :Journal of experimental and clinical medicine 2021

While mild gastrointestinal bleeding is common in Crohn's disease, massive extremely rare. In this case, we present a patient who presented with lower bleeding. A literature review of such rare presentation disease will be discussed.

Journal: :Journal of Geriatric Neurology 2023

Superficial siderosis (SS) of the central nervous system is a rare disorder caused by chronic or recurrent hemorrhages into subarachnoid space, and subsequent deposition hemosiderin in subpial layers brain spinal cord lead to development neuronal damage. The diagnosis SS typically made imaging management may include identifying treating underlying cause bleeding, as well symptomatic treatment. ...

Journal: :Nature 1969

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