Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of preand postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that it underlies learning and information storage in the brain, as well as the development and refinement of neuronal circuits during brain develop...

Synaptic strength depresses for low, and potentiates for high activation of the postsynaptic neuron. This feature is a key property of the well-known Bienenstock-Cooper-Munro (BCM) synaptic rule, which has been shown to maximize the selectivity of the postynaptic neuron, and thereby offers a possible explanation for experience-dependent cortical plasticity such as orientation selectivity. Howev...

Synaptic strength depresses for low and potentiates for high activation of the postsynaptic neuron. This feature is a key property of the Bienenstock-Cooper-Munro (BCM) synaptic learning rule, which has been shown to maximize the selectivity of the postsynaptic neuron, and thereby offers a possible explanation for experience-dependent cortical plasticity such as orientation selectivity. However...

Self-Assembled Nanostructures In article number 2107925, Ender Ercan, Wen-Chang Chen, and co-workers introduce self-assembled nanostructures of perovskite (CsPbBr3) quantum dot (QD)/poly(3-hexylthiophene) (P3HT) composite nanofibrils to understand the morphology/optoelectronic relationship. The photonic artificial synapse exhibits fundamental functions, including short-term plasticity, long-ter...

We show that continuum models for ideal plasticity can be obtained as a rigorous mathematical limit starting from a discrete microscopic model describing a viscoelastic crystal lattice with quenched disorder. The constitutive structure changes as a result of two concurrent limiting procedures: the vanishing-viscosity limit and the discrete-to-continuum limit. In the course of these limits a non...

Neural circuits are endowed with several forms of intrinsic and synaptic plasticity that could contribute to adaptive changes in behavior, but circuit complexities have hindered linking specific cellular mechanisms with their behavioral consequences. Eye movements generated by simple brainstem circuits provide a means for relating cellular plasticity to behavioral gain control. Here we show tha...