Aim: Reactive hyperplasias are often encountered tumor-like exophytic lesions of the oral mucosa, but they not a neoplasm. Local factors such as dental calculus, food residue stuck between teeth, incompatible prosthetic restoration, and systemic hormonal changes play role in etiology these hyperplasia. The aim this presentation is to evaluate possible etiological factors, clinical, radiological...

A patient with seropositive rheumatoid arthritis and a carrier of hepatitis B surface antigen developed angiofollicular hyperplasia (multicentric Castleman's disease). The hepatitis B virus and the rheumatoid factor may have had a role in the aetiology of this lymphatic disorder. The development of Castleman's disease in association with these factors may provide another clue supporting the rea...

Difficulty ill the histopathological sepitratiou of atypical reactive hyperplasia "f the lyniplioreticular system from neoplasia is not new. Such difficulty has led to the nosological existence of peculiar tumors whieh have defied precise tla.ssifioation. Tlioso oc-cuning in the ^gastrointestinal tract have been designated "psoudoleukemia gastrointestinalis"\ "unclassified lymplioma"^ and "pseu...

BACKGROUND Nasopharyngeal carcinoma (NPC) involves the orbits through direct extension to the orbital apex via the cavernous sinus. Anterior orbital masses are very rare with only a few anecdotes in the literature about an anterior spread via nasal cavity or tumour arising de novo from the lacrimal sac. Reactive lymphoid hyperplasia in the orbit has never been reported in association with NPC. ...

: Benign prostatic hyperplasia (BPH) is the overgrowth of prostate tissues with high prevalence in older men. BPH pathogenesis is not completely understood, but it is believed to be a result of de novo overgrowth of prostatic stroma. In this study, we show that aberrant activation of transforming growth factor-β (TGF-β) mobilizes mesenchymal/stromal stem cells (MSCs) in circulating blood, which...

BACKGROUND Non-reactive platelet counts elevation occurs mainly in myeloproliferative disorders (MPDs), which have been reported to be closely associated with JAK2 V617F mutation. Complete blood cell count (CBC) is essential in diagnosis of MPDs, however, the impact of JAK2 V617F mutation on the patients' hemogram variation remains not clear. METHODS JAK2 V617F mutation was detected by allele...

A pyogenic granuloma is a prevalent inflammatory hyperplasia of connective tissue. These lesions develop as reactive tissue response to low-grade local irritation, trauma, and hormonal imbalances. Morphologically, it may present single exophytic nodule or sessile papule, with smooth lobulated surface, on pedunculated base. hemorrhagic range in size from few millimeters several centimetres vary ...

AIMS In the gastric antrum and body, foveolar hyperplasia is a feature of reactive gastritis resulting from--for example, duodenogastric bile reflux and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to examine the occurrence and clinical relevance of gastric cardiac foveolar hyperplasia. METHODS The study population was drawn from a consecutive series of...

Topical application of the tumor promoter 12-0-tetradecanoylphorbol13-acetate (TPA) to SENCAR mouse skin results within 48 h in a 3-fold elevation of xanthine oxidase (XO) activity, an enzyme capable of gen erating the reactive oxygen species Superoxide and hydrogen peroxide. The antiinflammatory steroid fluocinolone acetonide, an inhibitor of TPAinduced hyperplasia, as well as the multiple sta...

Reactive C-cell hyperplasia (CCH) has been observed in cases of autoimmune Hashimoto's thyroiditis; however, its occurrence in Graves' disease, the other major autoimmune disorder, has not yet been investigated. On the other hand, although Carcinoembryonic Antigen (CEA) serum levels have been reported elevated in patients with autoimmune thyroid disease (ATD), the source of CEA production at th...