I vividly remember how pleased I was when Circulation Research published my first papers, one on the ventricular refractory period following changes in heart rate and another on the dual inputs into the atrioventricular node, in 1969. I thought then that Circulation Research was the top journal for basic research in the cardiovascular field, and I still think so today. Many things have changed ...

As the main drive components of the automobile transmission, the performance of gear shaft plays an important role on transmission performance. Aiming at the existing problems of the traditional strength check method of gear shaft, the objective of this study is to take a five-speed transmission as an example, to accomplish the strength analysis of gear shaft of the automobile transmission base...

In this study, rotating flexible shaft-disk system having flexible beams is considered as a dynamic system. After neglecting nonlinear terms, torsional vibration of the shaft-disk system and lateral and longitudinal vibration of the flexible beam are still coupled through the motor speed. The system has three natural frequencies; the flexible shaft-disk system torsional natural frequency, the f...

Cell migration can be considered as a repeated cycle of membrane protrusion and attachment, cytoskeletal contraction and rear detachment. At intermediate and high levels of cell-substratum adhesiveness, cell speed appears to be rate-limited by rear detachment, specifically by the disruption of cytoskeleton-adhesion receptor-extracellular matrix (ECM) linkages. Often, cytoskeletal linkages fract...

In 2009, the regulations for the Formula One World Championship were amended to allow the use of kinetic energy recovery systems (KERS). The new regulations stipulated that the KERS drive shaft be limited to the rear wheels, that output should be no more than 60 kW, and that the amount of energy used per lap be no more than 400 kJ. Honda had been conducting R&D in this area since the summer of ...

OBJECTIVE Signalized intersections are accident-prone areas especially for rear-end crashes due to the fact that the diversity of the braking behaviors of drivers increases during the signal change. The objective of this article is to improve knowledge of the relationship between rear-end crashes occurring at signalized intersections and a series of potential traffic risk factors classified by ...

Strain wedge (SW) model formulation has been used, in previous work, to evaluate the response of a single pile or a group of piles (including its pile cap) in layered soils to lateral loading. The SW model approach provides appropriate prediction for the behavior of an isolated pile and pile group under lateral static loading in layered soil (sand and/or clay). The SW model analysis covers the ...

  Background: Fractures of the femoral shaft are mostly the result of high-energy accidents that also cause multiple trauma injuries, in particular ipsilateral knee and hip injuries. The purpose of this study was to investigate the incidence of injuries associated with femoral shaft fractures and how many of them were undetected. Methods: We studied 148 patients (150 femoral shaft fractures) wi...

This chapter summarizes the performance of NEVEL during testing and competition. Attention is given to the design goals set forth in chapter 3. Numerous challenges encountered during testing are also discussed. The mechanical, sensor and navigation issues will be covered in order. 6.1 Mechanical Performance NEVEL's mechanical construction proved to be quite robust. The " T-Frame " was fabricate...

This chapter summarizes the performance of NEVEL during testing and competition. Attention is given to the design goals set forth in chapter 3. Numerous challenges encountered during testing are also discussed. The mechanical, sensor and navigation issues will be covered in order. 6.1 Mechanical Performance NEVEL's mechanical construction proved to be quite robust. The " T-Frame " was fabricate...