OBJECTIVE To assess the efficacy of various medications in the prevention of recurrent febrile seizures. STUDY DESIGN A meta-analysis of all published randomized, placebo-controlled trials of the preventive treatment of febrile seizures published in English; 45 articles were found, but only 9 trials were randomized and placebo-controlled--4 using phenobarbital; 3, diazepam; 1, pyridoxine; and...

A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term no perinatal complications. had normal growth and developmental milestones until at the age 7 months when he developed febrile status epilepticus. Since then, residual hemiplegia, dysarthria, cognitive delay se...

abstract objective febrile convulsions (fc) are the most common convulsive events in childhood, occurring in 2-5% of children. about one third of these children will have  a recurrence during a subsequent febrile infection. this sudden neurologic problem is extremely frightening and emotionally traumatic for parents so some physicians try to prevent recurrence of fc by prescribing different dru...

OBJECTIVE Simple Febrile Seizure (SFS) is the most common seizure disorder in childhood, and is frequently described as inoffensive disorder. Nevertheless, there is evidence suggesting the association between neonatal febrile seizures and hippocampal abnormalities in adulthood. This study was conducted at evaluating the hippocampal expression of pro-apoptotic Bax and anti-apoptotic Bcl-2 protei...

We conducted this study to determine the role of iron deficiency as a risk factor for first febrile seizure in children. Fifty children between 6 months to 6 years with first febrile seizure (Cases) and 50 children with febrile illness but without convulsions (Controls) were enrolled from the pediatric ward of a tertiary care hospital. Iron deficiency was determined by estimation of hemoglobin,...

BACKGROUND Since clinical signs of meningeal irritation in infants may be absent or misleading, the American Academy of Pediatrics in 1996 recommended that a lumbar puncture be performed in young children following a febrile seizure. Recent evidence supports a conservative approach in children who do not look ill at the time of the physician's assessment. Moreover, seizures as the presenting or...