The first critical stage in salamander or teleost appendage regeneration is creation of a specialized epidermis that instructs growth from underlying stump tissue. Here, we performed a forward genetic screen for mutations that impair this process in amputated zebrafish fins. Positional cloning and complementation assays identified a temperature-sensitive allele of the ECM component laminin beta...

New generation biomaterials for bone regeneration should be highly bioactive, resorbable and mechanically strong. Mesoporous bioactive glass (MBG), a novel bioactive material, has been used to study bone regeneration due to its excellent bioactivity, degradation and drug delivery ability, however, the construction of three-dimensional (3-D) MBG scaffolds (as for other bioactive inorganic scaffo...

Abstract Aims We studied the regeneration dynamics of woodlands and abandoned old fields in a landscape dominated by Quercus suber its lower limits rainfall temperature. Two hypotheses were established: (1) species is strongly favored presence tree cover; (2) growth Q. driven climatic variables that represent ecological limit leading distribution edge. Methods selected with without remnants ( n...

This paper reports a complete ammonia borane (AB) regeneration process in which Bu3SnH was utilized as a reductant for the reductive dechlorination of BCl3, and Et2PhN was selected as a 'helper ligand' to generate Et2PhN·BH3, which gives rise to a high yield of AB by a base-exchange reaction at ambient temperature.

In this study, the performance of an adsorbent coated finned tube exchanger for carbon capture was investigated numerically. The results showed that this structure has a great potential for being applied as a medium for CO2 capture by rapid indirect thermal swing adsorption. By using this structure, the recovery of 96%, and purity of 98% were achieved with a simple cycle consisting of two steps...

Burns and other severe skin injuries alter cutaneous perception of pain, temperature, and touch. During skin wound healing, peripheral nerve regeneration can occur from nerve endings of the wound bed, however, a functional recovery after an injury is often not sufficient due to scar formation or impaired wound healing.

Periodontitis is a chronic inflammatory disease that induces the destruction of tooth-supporting tissues, followed by tooth loss. Although several approaches have been applied to periodontal regeneration, complete periodontal regeneration has not been accomplished. Tissue engineering using a combination of cells and scaffolds is considered to be a viable alternative strategy. We have shown that...

Polyurethanes have been broadly used as biomaterials in tissue repair and regeneration due to their preeminent biocompatibility mechanical properties. However, traditional polyurethanes are not able efficiently cope with the complexity of dynamic microenvironments during process disease therapy. Physiologically responsive responding or reacting biological signals pathological abnormalities can ...