the effect of massage therapy on the quality of sleep in women with multiple sclerosis being admitted by isfahan m.s. association bahraini s , naji sa* , mannani r , bekhradi r received: 25 april, 2010 accepted: 27 july, 2010 abstract background & aims: low quality of sleep is one of the most common signs in multiple sclerosis that can result in reducing the quality of life, increasing mortalit...

AIMS To evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of subcutaneous peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis (RRMS) in the phase 3 ADVANCE study (n = 1512). METHODS During year 1, patients were randomized (1:1:1) to placebo or peginterferon beta-1a 125 μg every 2 or 4 weeks. After year 1, patients randomized to placebo were re-randomized t...

Nuclear factor erythroid 2-related 2 (NRF2; encoded by NFE2L2) is an inducible transcription that regulates the expression of a large network genes encoding proteins with cytoprotective functions. NRF2 also has role in maintenance mitochondrial and protein homeostasis, its activation allows adaptation to numerous types cellular stress. principally regulated at stability level three main ubiquit...

arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

adult neurogenesis is a process of producing nerve cells from their progenitor that occurs in some areas in the brain such as the hypothalamus. low activity in this area plays a role in neural degeneration and diseases such as multiple sclerosis, epilepsy and depression. ms is a neurodegenerative disease with a permanent disability that the main reason for it is axonal degeneration and neuronal...

multiple sclerosis (ms) is an inflammatory disorder, in which neurons become demyelinated. to date, its etiology has remained unknown. nevertheless, certain features are inspected to provoke ms. for instance, improper function of immune cells is widely believed to be the basis of such disorder. in this concept, ms is stated as an autoimmune disease, which was asserted by major of studies, as cd...

neuroinflammation is a disorder that causes neurological disease. neuroinflammation has a significant role in induce of multiple sclerosis (ms) and one of the situations that must be treated stops the ongoing process of inflammation against the cns by self-reactive lymphocytes. according to the successful results that were obtained from the pre-clinical phase of cell therapy, many studies were ...

multiple sclerosis (ms) is an autoimmune inflammatory process that affects the central nervous system (cns). celiac disease (cd) is a systemic autoimmune disorder of gluten intolerance. based on the presumed association of ms with multiple autoimmune processes, the coincidence of ms with gluten sensitivity has been investigated with controversial results. here, we report a known case of ms with...

objectives: multiple sclerosis is one of the most important and prevalent central nervous system diseases, causing disorders such as depression among affected patients. positive psychotherapy is also a new approach that can be effective in reducing the depression of these people. this study aims to investigate the efficiency of group positive psychotherapy for decreasing the depression among fe...