THE ROLE of the kidney in the regulation of arterial pressure was recognized as early as 1898 when Tigerstedt and Bergman demonstrated that kidney extracts possess a pressor action and gave the name renin to the substance producing the action. In 1934. Goldblatt and co-workers' produced chronic renal hypertension in dogs by renal artery constriction. This discovery was a major breakthrough beca...

Atherosclerotic renovascular disease (ARVD) is a major cause of secondary hypertension, especially in the elderly population. ARVD typically involves the proximal third of the renal artery including the perirenal aorta and ostium. The prevalence of ARVD is about 6.3–6.8 % in patients undergoing angiography or as determined in a population-based study utilizing a noninvasive screening technique ...

these patients,' but we found this not to be the case. Our findings accord with those of Dustan et al, who found that most patients with angiographic evidence of renal artery disease did not have hypertension.3 It could be argued that angiographic evidence of renal artery disease does not necessarily indicate a functionally important stenosis, hence the poor relation between angiographic findin...

 Etiology: CKD is the terminal stage of chronic progressive nephropathies which include: 1. Glomerular nephropathies:  severe glomerulonephritis (80% of CKD cases)  diabetic nephropathy  renal amyloidosis 2. Renal vascular nephropathies:  malignant hypertension  hypertension nephroangiosclerosis  bilateral renal artery sclerosis 3. Tubulointerstitial nephropathies  chronic pyelonephriti...

AIM There is lot of controversy regarding the efficacy of renal artery stenting in atherosclerotic renal artery stenosis. The aim of this retrospective study is to evaluate blood pressure control and requirement of antihypertensive drugs after renal artery stenting. METHODS AND RESULTS Eighty patients who have undergone renal artery stenting for atherosclerotic renal artery stenosis with hype...

1. The injection of trypsin into both renal arteries of the dog was found to cause an acute necrosis of large sections of the kidney, an immediate excretory insufficiency, and a transient hypertension. 2. Dogs surviving the acute phase of the trypsin injection, developed a chronic renal excretory insufficiency with no hypertension, despite the severity and duration of the renal excretory insuff...