Although the definition of renal tubular acidosis (RTA) is simple, understanding the physiologic basis underlying the various types of this clinical entity is much more difficult. The pathophysiology of this disorder is reviewed using the normal acid-base functions of the involved segments of the nephron as a guide to understanding. Clinical and laboratory features of the subtypes of RTA are ad...

[This corrects the article on p. 424 in vol. 9, PMID: 27274828.].

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...

Renal tubular acidosis (RTA) is characterized by metabolic acidosis due to renal impaired acid excretion. Hyperchloremic acidosis with normal anion gap and normal or minimally affected glomerular filtration rate defines this disorder. RTA can also present with hypokalemia, medullary nephrocalcinosis and nephrolitiasis, as well as growth retardation and rickets in children, or short stature and ...

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...

We describe a case of acetazolamide induced acidosis associated with the precipitation of a hyperosmolar state in a diabetic patient 6 weeks after routine phacoemulsification. While renal tubular acidosis is well reported with acetazolamide, this case suggests that a direct diuresis induced acidosis can also have significant effects, producing serious complications when acetazolamide is prescri...