Abstract New developments in single-cell genomics have transformed developmental biology recent years by enabling systematic analysis of embryonic cell types and differentiation trajectories. Ongoing efforts experimental computational method development aim to reveal gene-regulatory mechanisms provide additional spatio-temporal information about fate decisions. Here, we discuss technological as...

Microarray technology has broadened the insight into many research fields allowing scientists to analyse the expression of many genes in quick and efficient experiments aimed at translating these findings into clinical applications. In reproductive medicine, researchers have exploited microarrays to increase understanding of the molecular mechanisms involved in endometrial receptivity and how a...

Although a species' locomotor capacity is suggestive of its ability to escape global climate change, such a suggestion is not necessarily straightforward. Species vary substantially in locomotor capacity, both ontogenetically and within/among populations, and much of this variation has a genetic basis. Accordingly, locomotor capacity can and does evolve rapidly, as selection experiments demonst...

Sheep and goat breeds are selected worldwide for meat, wool, and dairy production, and breeding objectives also include other functional traits such as reproductive performance and disease resistance. In early 2007, the development of next-generation sequencing (NGS) allowed de novo sequencing of sheep (Jiang et al., 2014) and goat genomes (Dong et al., 2013). In turn, it offered an opportunity...

Like all human individual differences, personality traits and intelligence are substantially heritable. From an evolutionary perspective, this poses the question what evolutionary forces maintain their genetic variation. Information about the genetic architecture and associations with evolutionary fitness permit inferences about these evolutionary forces. As our understanding of the genomics of...

Since the first domestication of livestock, people have been attempting to alter specific traits in animals that we deem to be desirable for various reasons. In doing, so we have been indirectly altering the genetic makeup of these species by selecting and breeding animals with specific traits, and therefore, particular genetic make-ups related to these traits. This initial form of genetic impr...

The review focuses on breeding practices aimed at improving resistance to diseases and health disorders that are associated with better efficiency, welfare longevity of cows. It is commonly known like mastitis, foot claw disorders, metabolic reproductive issues seriously violate dairy cows’ well-being. cause prevailing fertility deterioration has been the intensive selection merely based higher...

The elucidation, unravelling and understanding of the molecular basis of transcriptional control during preimplantation development is of utmost importance if we are to intervene and eliminate or reduce abnormalities associated with growth, disease and infertility by applying assisted reproduction. Importantly, these studies should enhance our knowledge of basic reproductive biology and its app...

1. Species of the genus Drosophila reproduce in a wide range of different resources, including fruits, sap, flowers, mushrooms and cacti. Drosophila species and their resources also exhibit considerable variability in geographic distribution. 2. Habitat and resource differences pose enormous challenges for Drosophila species. Host chemistry may include highly toxic compounds and breeding sites ...

Like all human individual differences, personality traits and intelligence are substantially heritable. From an evolutionary perspective, this poses the question what evolutionary forces maintain their genetic variation. Information about the genetic architecture and associations with evolutionary fitness permit inferences about these evolutionary forces. As our understanding of the genomics of...