PURPOSE. This study examined the relationship between high myopia and three myopia candidate genes, namely matrix metalloproteinase 2 (MMP2) and tissue inhibitor of metalloproteinase 2 and 3 (TIMP2 and TIMP3), involved in scleral remodeling. METHODS. The study recruited unrelated adult Han Chinese who were high myopes (spherical equivalent ≤-6.0D for both eyes; cases) and emmetropes (within ±1....

BACKGROUND Rapid-acting insulin analogs (RAIs) have not been examined for long-term safety in randomized clinical trials. We performed a nationwide longitudinal cohort study among individuals with type 2 diabetes (T2DM) to address cardiovascular safety and mortality among users of lispro, aspart and glulisine insulins. METHODS We used four national registers, following patients previously not...

The aim of this paper is to describe and reflect on an interactive research approach used to address the challenges on how to improve product introductions, the part of the product realization process associated with the transfer of a product from product development to serial production. In the interactive research approach, research results as well as improvement of practice are given equal i...

Recent studies in academic discourse show that rhetorical choices in student academic writing differ across disciplines. Focusing on the introductions of examination essays, the present study examines the rhetorical choices made by second-year undergraduates in Literature-in-English and Sociology courses in a Ghanaian state university. A combined framework comprising Swales‟ rhetorical move app...

Providing culturally and linguistically appropriate home healthcare and hospice care to patients who have emigrated from the African continent can be a challenge. This article reviews Web sites that provide introductions to some of the predominant cultures in Africa. Web sites providing patient education material in 13 African languages are also discussed.

Like conversation and other modes of communication, writing is a rich medium for gender performance. In fact, writing functions to construct the disciplines as well as the gender of its practitioners. Despite the significance of author gender, as one constitutive dimension of any writing, it has been relatively under-researched. One way, by means of which author gender is practiced, and reveale...

Baker and Stebbins's 1965 book The Genetics of Colonizing Species aimed to draw together scientists from a variety of disciplines to provide a conceptual framework for the study of species introductions. A goal of their volume was to examine how studies on biological invasions could be used to provide insight into basic research questions as well as to develop practical strategies for control. ...

Introductions of nonnative walleye (Stizostedion vitreum) and northern pike (Esox lucius) have created popular recreational fisheries in many Northwestern waters. Rising demand for expanded angling opportunities for these species, especially walleye, has been met with growing concern about longterm risks associated with the introduction of a top predator. Proposed introductions are often contro...

The value of distinguishing native from nonnative invasive species has recently been questioned. However, this dichotomy is important for understanding whether a species' successful dominance is caused by introductions, changing environmental conditions that facilitate an existing population, or both processes. We highlight the importance of knowing the origin of hard-to-detect invasive microor...